H3K36 Methylation and the Chromodomain Protein Eaf3 Are Required for Proper Cotranscriptional Spliceosome Assembly

H3K36 Methylation and the Chromodomain Protein Eaf3 Are Required for Proper Cotranscriptional Spliceosome Assembly

Summary: In the eukaryotic cell, spliceosomes assemble onto pre-mRNA cotranscriptionally. Spliceosome assembly takes place in the context of the chromatin environment, suggesting that the state of the chromatin may affect splicing. The molecular details and mechanisms through which chromatin affects...

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Bibliographic Details
Main Authors:	Calvin S. Leung, Stephen M. Douglass, Marco Morselli, Matthew B. Obusan, Marat S. Pavlyukov, Matteo Pellegrini, Tracy L. Johnson
Format:	Article
Language:	English
Published:	Elsevier 2019-06-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124719307399

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