Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA)
Introduction: Antimicrobial agents are essentially important in reducing the global burden of infectious diseases. With the irrational and excessive use of antibiotics in underdeveloped and developing countries, there may be chances to develop and spread resistant pathogens in the community. As...
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/10347/30085_CE[Ra]_F(Sh)_PF1(NE_VT_SS)_PFA(NE_SS).pdf |
| _version_ | 1811214670040662016 |
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| author | Guruvu Neeraja Rani Radhika Budumuru Narasinga Rao Bandaru |
| author_facet | Guruvu Neeraja Rani Radhika Budumuru Narasinga Rao Bandaru |
| author_sort | Guruvu Neeraja Rani |
| collection | DOAJ |
| description | Introduction: Antimicrobial agents are essentially important
in reducing the global burden of infectious diseases. With the
irrational and excessive use of antibiotics in underdeveloped
and developing countries, there may be chances to develop
and spread resistant pathogens in the community. As a result,
the effectiveness of the antibiotics is diminishing. Therefore, the
need for novel alternative antimicrobial strategies has renewed
interest in natural products like turmeric, honey, ginger and
others exhibiting antibacterial properties. This situation has led
to a re-evaluation of the therapeutic use of ancient remedies
like honey as no other studies are available in the state of
Andhra Pradesh with the locally available honey.
Aim: To find out the efficacy of antibacterial activity of locally
available honey against Methicillin Resistant Staphylococcus
aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus
(MSSA) isolates.
Materials and Methods: A prospective study on the
antibacterial activity of Bharat multi floral pasteurised honey
which was locally available in the state of Andhra Pradesh,
further it was conducted and evaluated against the bacterial
strains of Methicillin Resistant Staphylococcus aureus and
Methicillin Sensitive Staphylococcus aureus. Their antibacterial
sensitivity pattern was tested using Kirby-Bauer disc diffusion
susceptibility testing technique of CLSI along with other
commonly used antimicrobials.
Results: Both MRSA and MSSA isolates were sensitive to
honey. But MRSA were resistant to all antimicrobials tested
except linezolid where as MSSA were sensitive to all except
penicillin.
Conclusion: It is definitely worthy to consider honey as a
promising future antimicrobial to be tested and studied. Honey,
may be elaborately used in future with some more molecular
studies on its method of action as an antimicrobial agent. |
| first_indexed | 2024-04-12T06:08:49Z |
| format | Article |
| id | doaj.art-d857b7a4c9dd4f0d8f21f98b9a62bd3b |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-12T06:08:49Z |
| publishDate | 2017-08-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-d857b7a4c9dd4f0d8f21f98b9a62bd3b2022-12-22T03:44:47ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-08-01118DC05DC0810.7860/JCDR/2017/30085.10347Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA)Guruvu Neeraja Rani0Radhika Budumuru1Narasinga Rao Bandaru2Research Scholar, Saveetha University, Chennai, Tamil Nadu, India.Assistant Professor, Department of Microbiology, Great Eastern Medical School, Srikakulam, Andhra Pradesh, India.Professor and Head, Department of Microbiology, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh, India.Introduction: Antimicrobial agents are essentially important in reducing the global burden of infectious diseases. With the irrational and excessive use of antibiotics in underdeveloped and developing countries, there may be chances to develop and spread resistant pathogens in the community. As a result, the effectiveness of the antibiotics is diminishing. Therefore, the need for novel alternative antimicrobial strategies has renewed interest in natural products like turmeric, honey, ginger and others exhibiting antibacterial properties. This situation has led to a re-evaluation of the therapeutic use of ancient remedies like honey as no other studies are available in the state of Andhra Pradesh with the locally available honey. Aim: To find out the efficacy of antibacterial activity of locally available honey against Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) isolates. Materials and Methods: A prospective study on the antibacterial activity of Bharat multi floral pasteurised honey which was locally available in the state of Andhra Pradesh, further it was conducted and evaluated against the bacterial strains of Methicillin Resistant Staphylococcus aureus and Methicillin Sensitive Staphylococcus aureus. Their antibacterial sensitivity pattern was tested using Kirby-Bauer disc diffusion susceptibility testing technique of CLSI along with other commonly used antimicrobials. Results: Both MRSA and MSSA isolates were sensitive to honey. But MRSA were resistant to all antimicrobials tested except linezolid where as MSSA were sensitive to all except penicillin. Conclusion: It is definitely worthy to consider honey as a promising future antimicrobial to be tested and studied. Honey, may be elaborately used in future with some more molecular studies on its method of action as an antimicrobial agent.https://jcdr.net/articles/PDF/10347/30085_CE[Ra]_F(Sh)_PF1(NE_VT_SS)_PFA(NE_SS).pdfantibacterial activitykirby-bauer disc diffusionminimum inhibitory concentrationzone of inhibition |
| spellingShingle | Guruvu Neeraja Rani Radhika Budumuru Narasinga Rao Bandaru Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) Journal of Clinical and Diagnostic Research antibacterial activity kirby-bauer disc diffusion minimum inhibitory concentration zone of inhibition |
| title | Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) |
| title_full | Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) |
| title_fullStr | Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) |
| title_full_unstemmed | Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) |
| title_short | Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) |
| title_sort | antimicrobial activity of honey with special reference to methicillin resistant staphylococcus aureus mrsa and methicillin sensitive staphylococcus aureus mssa |
| topic | antibacterial activity kirby-bauer disc diffusion minimum inhibitory concentration zone of inhibition |
| url | https://jcdr.net/articles/PDF/10347/30085_CE[Ra]_F(Sh)_PF1(NE_VT_SS)_PFA(NE_SS).pdf |
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