Drosophila SETDB1 is required for chromosome 4 silencing.
Histone H3 lysine 9 (H3K9) methylation is associated with gene repression and heterochromatin formation. In Drosophila, SU(VAR)3-9 is responsible for H3K9 methylation mainly at pericentric heterochromatin. However, the histone methyltransferases responsible for H3K9 methylation at euchromatic sites,...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-05-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1866353?pdf=render |