CDKN2AIP is critical for spermiogenesis and germ cell development

CDKN2AIP is critical for spermiogenesis and germ cell development

Abstract Background As a member of RNA-binding protein, CDKN2AIP has been shown to play a critical role in stem cell pluripotency and somatic differentiation. Recent studies indicate that Cdkn2aip is essential for spermatogonial self-renewal and proliferation through the activating Wnt-signaling pat...

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Bibliographic Details
Main Authors: Yuming Cao, Qi Sun, Zhenlie Chen, Jing Lu, Ting Geng, Ling Ma, Yuanzhen Zhang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Cell & Bioscience
Subjects:
Spermiogenesis
Germ cell development
DNA double-strand break repair
Protamine replacement
Male infertility
Online Access:https://doi.org/10.1186/s13578-022-00861-z

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