How to Prevent Aseptic Loosening in Cementless Arthroplasty: A Review

Aseptic loosening is the main late postoperative complication of cementless total hip arthroplasties (THAs), leading to pain and functional impairment. This article aims to update the orthopedic surgeon on the various methods by which the aseptic loosening rate can be reduced. We performed a systema...

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Main Authors: Dragos Apostu, Doina Piciu, Daniel Oltean-Dan, Dan Cosma, Ondine Lucaciu, Catalin Popa, Alexandru Mester, Horea Benea
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/12/3/1571
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author Dragos Apostu
Doina Piciu
Daniel Oltean-Dan
Dan Cosma
Ondine Lucaciu
Catalin Popa
Alexandru Mester
Horea Benea
author_facet Dragos Apostu
Doina Piciu
Daniel Oltean-Dan
Dan Cosma
Ondine Lucaciu
Catalin Popa
Alexandru Mester
Horea Benea
author_sort Dragos Apostu
collection DOAJ
description Aseptic loosening is the main late postoperative complication of cementless total hip arthroplasties (THAs), leading to pain and functional impairment. This article aims to update the orthopedic surgeon on the various methods by which the aseptic loosening rate can be reduced. We performed a systematic review by searching the PubMed database for hip aseptic loosening. We included meta-analysis, randomized controlled trials, reviews, and systematic reviews in the last 10 years, which provided information on techniques that can prevent aseptic loosening in total hip arthroplasty. From a total of 3205 articles identified, 69 articles (2%) met the inclusion criteria, leading to a total of 36 recommendations. A lot of research has been conducted in terms of septic loosening in the last decade. Currently, we have various techniques by which we can reduce the rate of aseptic loosening. Nevertheless, further randomized clinical trials are needed to expand the recommendations for aseptic loosening prevention.
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spelling doaj.art-d860bd5383dc438dac994615e3e81b2f2023-11-23T15:59:49ZengMDPI AGApplied Sciences2076-34172022-02-01123157110.3390/app12031571How to Prevent Aseptic Loosening in Cementless Arthroplasty: A ReviewDragos Apostu0Doina Piciu1Daniel Oltean-Dan2Dan Cosma3Ondine Lucaciu4Catalin Popa5Alexandru Mester6Horea Benea7Department of Orthopaedics and Traumatology, University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaNuclear Medicine Department, University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Orthopaedics and Traumatology, University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Orthopaedics and Traumatology, University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Oral Rehabilitation, University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Materials Science and Engineering, Technical University of Cluj-Napoca, 400641 Cluj-Napoca, RomaniaDepartment of Oral Rehabilitation, University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Orthopaedics and Traumatology, University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaAseptic loosening is the main late postoperative complication of cementless total hip arthroplasties (THAs), leading to pain and functional impairment. This article aims to update the orthopedic surgeon on the various methods by which the aseptic loosening rate can be reduced. We performed a systematic review by searching the PubMed database for hip aseptic loosening. We included meta-analysis, randomized controlled trials, reviews, and systematic reviews in the last 10 years, which provided information on techniques that can prevent aseptic loosening in total hip arthroplasty. From a total of 3205 articles identified, 69 articles (2%) met the inclusion criteria, leading to a total of 36 recommendations. A lot of research has been conducted in terms of septic loosening in the last decade. Currently, we have various techniques by which we can reduce the rate of aseptic loosening. Nevertheless, further randomized clinical trials are needed to expand the recommendations for aseptic loosening prevention.https://www.mdpi.com/2076-3417/12/3/1571aseptic looseningtotal hip arthroplastytotal hip replacementosseointegration
spellingShingle Dragos Apostu
Doina Piciu
Daniel Oltean-Dan
Dan Cosma
Ondine Lucaciu
Catalin Popa
Alexandru Mester
Horea Benea
How to Prevent Aseptic Loosening in Cementless Arthroplasty: A Review
Applied Sciences
aseptic loosening
total hip arthroplasty
total hip replacement
osseointegration
title How to Prevent Aseptic Loosening in Cementless Arthroplasty: A Review
title_full How to Prevent Aseptic Loosening in Cementless Arthroplasty: A Review
title_fullStr How to Prevent Aseptic Loosening in Cementless Arthroplasty: A Review
title_full_unstemmed How to Prevent Aseptic Loosening in Cementless Arthroplasty: A Review
title_short How to Prevent Aseptic Loosening in Cementless Arthroplasty: A Review
title_sort how to prevent aseptic loosening in cementless arthroplasty a review
topic aseptic loosening
total hip arthroplasty
total hip replacement
osseointegration
url https://www.mdpi.com/2076-3417/12/3/1571
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