How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular Research
Caffeine substantially affects cardiovascular functioning, yet wide variability exists in caffeine control procedures in cardiovascular reactivity research. This study was conducted in order to identify a minimal abstention duration in habitual coffee consumers whereby cardiovascular reactivity is u...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/13/2/224 |
| _version_ | 1797622022995443712 |
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| author | Shara S. Grant Kye Kim Bruce H. Friedman |
| author_facet | Shara S. Grant Kye Kim Bruce H. Friedman |
| author_sort | Shara S. Grant |
| collection | DOAJ |
| description | Caffeine substantially affects cardiovascular functioning, yet wide variability exists in caffeine control procedures in cardiovascular reactivity research. This study was conducted in order to identify a minimal abstention duration in habitual coffee consumers whereby cardiovascular reactivity is unconfounded by caffeine; Six hours (caffeine’s average half-life) was hypothesized. Thirty-nine subjects (mean age: 20.9; 20 women) completed a repeated measures study involving hand cold pressor (CP) and memory tasks. Caffeinated and decaffeinated coffee were administered. The following cardiovascular indices were acquired during pre-task, task, and post-task epochs prior to coffee intake, 30 min-, and six hours post-intake: Heart rate (HR), high-frequency heart rate variability (HF-HRV), root mean squared successive differences (RMSSD), systolic and diastolic blood pressures (SBP, DBP), mean arterial pressure (MAP), pre-ejection period (PEP), left ventricular ejection time (LVET), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI). Results support the adequacy of a six-hour abstention in controlling for caffeine-elicited cardiovascular changes. The current study offers a suggested guideline for caffeine abstention duration in cardiovascular research in psychophysiology. Consistent practice in caffeine abstention protocols would promote validity and reliability across such studies. |
| first_indexed | 2024-03-11T09:05:24Z |
| format | Article |
| id | doaj.art-d8651bc9430e495c9aeb15595fe2c8e4 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-11T09:05:24Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-d8651bc9430e495c9aeb15595fe2c8e42023-11-16T19:27:58ZengMDPI AGBrain Sciences2076-34252023-01-0113222410.3390/brainsci13020224How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular ResearchShara S. Grant0Kye Kim1Bruce H. Friedman2Department of Psychology, Virginia Tech, 109 Williams Hall, Blacksburg, VA 24061, USADepartment of Psychiatry and Behavioral Medicine, Virginia Tech Carilion Clinic School of Medicine, 1 Riverside Circle, Roanoke, VA 24016, USADepartment of Psychology, Virginia Tech, 109 Williams Hall, Blacksburg, VA 24061, USACaffeine substantially affects cardiovascular functioning, yet wide variability exists in caffeine control procedures in cardiovascular reactivity research. This study was conducted in order to identify a minimal abstention duration in habitual coffee consumers whereby cardiovascular reactivity is unconfounded by caffeine; Six hours (caffeine’s average half-life) was hypothesized. Thirty-nine subjects (mean age: 20.9; 20 women) completed a repeated measures study involving hand cold pressor (CP) and memory tasks. Caffeinated and decaffeinated coffee were administered. The following cardiovascular indices were acquired during pre-task, task, and post-task epochs prior to coffee intake, 30 min-, and six hours post-intake: Heart rate (HR), high-frequency heart rate variability (HF-HRV), root mean squared successive differences (RMSSD), systolic and diastolic blood pressures (SBP, DBP), mean arterial pressure (MAP), pre-ejection period (PEP), left ventricular ejection time (LVET), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI). Results support the adequacy of a six-hour abstention in controlling for caffeine-elicited cardiovascular changes. The current study offers a suggested guideline for caffeine abstention duration in cardiovascular research in psychophysiology. Consistent practice in caffeine abstention protocols would promote validity and reliability across such studies.https://www.mdpi.com/2076-3425/13/2/224caffeinecoffeecardiovascularmethodologyautonomic |
| spellingShingle | Shara S. Grant Kye Kim Bruce H. Friedman How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular Research Brain Sciences caffeine coffee cardiovascular methodology autonomic |
| title | How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular Research |
| title_full | How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular Research |
| title_fullStr | How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular Research |
| title_full_unstemmed | How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular Research |
| title_short | How Long Is Long Enough? Controlling for Acute Caffeine Intake in Cardiovascular Research |
| title_sort | how long is long enough controlling for acute caffeine intake in cardiovascular research |
| topic | caffeine coffee cardiovascular methodology autonomic |
| url | https://www.mdpi.com/2076-3425/13/2/224 |
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