MAIT Cells Display a Specific Response to Type 1 IFN Underlying the Adjuvant Effect of TLR7/8 Ligands

MAIT Cells Display a Specific Response to Type 1 IFN Underlying the Adjuvant Effect of TLR7/8 Ligands

Mucosal-associated invariant T (MAIT) cells constitute a highly conserved subset of effector T cells with innate-like recognition of a wide array of bacteria and fungi in humans. Harnessing the potential of these cells could represent a major advance as a new immunotherapy approach to fight difficul...

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Bibliographic Details
Main Authors: Marion Pavlovic, Christelle Gross, Chahinaize Chili, Thomas Secher, Emmanuel Treiner
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
MAIT cells
type 1 interferons
co-stimulation
cytokines
vaccines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02097/full

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