The role of varicocele repair in the new era of assisted reproductive technology

Infertility affects 10-15% of couples who are trying to conceive, and half of the cases are due to male infertility. Intracytoplasmic sperm injection is increasingly being used to overcome multiple sperm deficiencies. Due to its effectiveness, some have proposed ICSI as a solution for all cases of m...

Full description

Bibliographic Details
Main Authors: Marcello Cocuzza, Mariana Amora Cocuzza, Frances Monette Papa Bragais, Ashok Agarwal
Format: Article
Language:English
Published: Elsevier España 2008-01-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322008000300018
_version_ 1811229066355802112
author Marcello Cocuzza
Mariana Amora Cocuzza
Frances Monette Papa Bragais
Ashok Agarwal
author_facet Marcello Cocuzza
Mariana Amora Cocuzza
Frances Monette Papa Bragais
Ashok Agarwal
author_sort Marcello Cocuzza
collection DOAJ
description Infertility affects 10-15% of couples who are trying to conceive, and half of the cases are due to male infertility. Intracytoplasmic sperm injection is increasingly being used to overcome multiple sperm deficiencies. Due to its effectiveness, some have proposed ICSI as a solution for all cases of male infertility, regardless of the cause. Hence, even men with potentially treatable causes of infertility have sought the aid of assisted reproductive technology, rather than undergo specific therapies to treat their infertility. Varicoceles are the most frequent physical finding in infertile men; indeed, they may be responsible for nearly one-third of cases of male infertility. Varicocele management, however, has always been a controversial issue because very few randomized, controlled studies have been performed to examine varicocelectomy as an infertility treatment. Significant evidence suggests that varicoceles have a harmful effect on the testis and that varicocelectomy can not only prevent progressive decline in testicular function but also reverse the damage. However, the degree to which varicocele repair improves pregnancy rates and the success of assisted reproductive technology remains controversial.
first_indexed 2024-04-12T10:08:17Z
format Article
id doaj.art-d86b046197fc4f338a7b04018c0f8386
institution Directory Open Access Journal
issn 1807-5932
1980-5322
language English
last_indexed 2024-04-12T10:08:17Z
publishDate 2008-01-01
publisher Elsevier España
record_format Article
series Clinics
spelling doaj.art-d86b046197fc4f338a7b04018c0f83862022-12-22T03:37:23ZengElsevier EspañaClinics1807-59321980-53222008-01-0163339540410.1590/S1807-59322008000300018The role of varicocele repair in the new era of assisted reproductive technologyMarcello CocuzzaMariana Amora CocuzzaFrances Monette Papa BragaisAshok AgarwalInfertility affects 10-15% of couples who are trying to conceive, and half of the cases are due to male infertility. Intracytoplasmic sperm injection is increasingly being used to overcome multiple sperm deficiencies. Due to its effectiveness, some have proposed ICSI as a solution for all cases of male infertility, regardless of the cause. Hence, even men with potentially treatable causes of infertility have sought the aid of assisted reproductive technology, rather than undergo specific therapies to treat their infertility. Varicoceles are the most frequent physical finding in infertile men; indeed, they may be responsible for nearly one-third of cases of male infertility. Varicocele management, however, has always been a controversial issue because very few randomized, controlled studies have been performed to examine varicocelectomy as an infertility treatment. Significant evidence suggests that varicoceles have a harmful effect on the testis and that varicocelectomy can not only prevent progressive decline in testicular function but also reverse the damage. However, the degree to which varicocele repair improves pregnancy rates and the success of assisted reproductive technology remains controversial.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322008000300018VaricoceleVaricocelectomyMale infertilitySeminal parametersAssisted reproductive techniques
spellingShingle Marcello Cocuzza
Mariana Amora Cocuzza
Frances Monette Papa Bragais
Ashok Agarwal
The role of varicocele repair in the new era of assisted reproductive technology
Clinics
Varicocele
Varicocelectomy
Male infertility
Seminal parameters
Assisted reproductive techniques
title The role of varicocele repair in the new era of assisted reproductive technology
title_full The role of varicocele repair in the new era of assisted reproductive technology
title_fullStr The role of varicocele repair in the new era of assisted reproductive technology
title_full_unstemmed The role of varicocele repair in the new era of assisted reproductive technology
title_short The role of varicocele repair in the new era of assisted reproductive technology
title_sort role of varicocele repair in the new era of assisted reproductive technology
topic Varicocele
Varicocelectomy
Male infertility
Seminal parameters
Assisted reproductive techniques
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322008000300018
work_keys_str_mv AT marcellococuzza theroleofvaricocelerepairintheneweraofassistedreproductivetechnology
AT marianaamoracocuzza theroleofvaricocelerepairintheneweraofassistedreproductivetechnology
AT francesmonettepapabragais theroleofvaricocelerepairintheneweraofassistedreproductivetechnology
AT ashokagarwal theroleofvaricocelerepairintheneweraofassistedreproductivetechnology
AT marcellococuzza roleofvaricocelerepairintheneweraofassistedreproductivetechnology
AT marianaamoracocuzza roleofvaricocelerepairintheneweraofassistedreproductivetechnology
AT francesmonettepapabragais roleofvaricocelerepairintheneweraofassistedreproductivetechnology
AT ashokagarwal roleofvaricocelerepairintheneweraofassistedreproductivetechnology