Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation
Abstract Congenital self‐healing Langerhans cell histiocytosis (CSHLCH) is a rare variant of Langerhans cell histiocytosis characterised by the presence of skin lesions in the neonate and spontaneous self‐healing after a variable period of time. We report three cases of CSHLCH with BRAF‐V600E mutati...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-03-01
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| Series: | JEADV Clinical Practice |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jvc2.14 |
| _version_ | 1817970995353354240 |
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| author | Mar Ramírez‐Lluch Isabel Colmenero José Suárez Saulo Carrión‐Marrero Francisco Rodríguez‐Fuertes Ana Mateos‐Mayo Ángela Hernández‐Martín Antonio Torrelo |
| author_facet | Mar Ramírez‐Lluch Isabel Colmenero José Suárez Saulo Carrión‐Marrero Francisco Rodríguez‐Fuertes Ana Mateos‐Mayo Ángela Hernández‐Martín Antonio Torrelo |
| author_sort | Mar Ramírez‐Lluch |
| collection | DOAJ |
| description | Abstract Congenital self‐healing Langerhans cell histiocytosis (CSHLCH) is a rare variant of Langerhans cell histiocytosis characterised by the presence of skin lesions in the neonate and spontaneous self‐healing after a variable period of time. We report three cases of CSHLCH with BRAF‐V600E mutation and high Ki‐67 proliferative activity. |
| first_indexed | 2024-04-13T20:41:10Z |
| format | Article |
| id | doaj.art-d86b73a2a4f74594b8f889ad093055b1 |
| institution | Directory Open Access Journal |
| issn | 2768-6566 |
| language | English |
| last_indexed | 2024-04-13T20:41:10Z |
| publishDate | 2022-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | JEADV Clinical Practice |
| spelling | doaj.art-d86b73a2a4f74594b8f889ad093055b12022-12-22T02:30:52ZengWileyJEADV Clinical Practice2768-65662022-03-0111535710.1002/jvc2.14Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutationMar Ramírez‐Lluch0Isabel Colmenero1José Suárez2Saulo Carrión‐Marrero3Francisco Rodríguez‐Fuertes4Ana Mateos‐Mayo5Ángela Hernández‐Martín6Antonio Torrelo7Department of Dermatology Hospital Infantil Universitario Niño Jesús Madrid SpainDepartment of Pathology Hospital Infantil Universitario Niño Jesús Madrid SpainDepartment of Dermatology Hospital Universitario Virgen de la Candelaria Santa Cruz de Tenerife SpainDepartment of Pathology Hospital Universitario Virgen de la Candelaria Santa Cruz de Tenerife SpainDepartment of Pediatrics Hospital de Valdepeñas SpainDepartment of Dermatology Hospital Infantil Universitario Niño Jesús Madrid SpainDepartment of Dermatology Hospital Infantil Universitario Niño Jesús Madrid SpainDepartment of Dermatology Hospital Infantil Universitario Niño Jesús Madrid SpainAbstract Congenital self‐healing Langerhans cell histiocytosis (CSHLCH) is a rare variant of Langerhans cell histiocytosis characterised by the presence of skin lesions in the neonate and spontaneous self‐healing after a variable period of time. We report three cases of CSHLCH with BRAF‐V600E mutation and high Ki‐67 proliferative activity.https://doi.org/10.1002/jvc2.14BRAF proteincongenital self‐healing Langerhans cell histiocytosishistiocytosisLangerhans cell histiocytosismitogen‐activated protein kinases (MAPKs) |
| spellingShingle | Mar Ramírez‐Lluch Isabel Colmenero José Suárez Saulo Carrión‐Marrero Francisco Rodríguez‐Fuertes Ana Mateos‐Mayo Ángela Hernández‐Martín Antonio Torrelo Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation JEADV Clinical Practice BRAF protein congenital self‐healing Langerhans cell histiocytosis histiocytosis Langerhans cell histiocytosis mitogen‐activated protein kinases (MAPKs) |
| title | Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation |
| title_full | Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation |
| title_fullStr | Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation |
| title_full_unstemmed | Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation |
| title_short | Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation |
| title_sort | three cases of congenital self healing langerhans cell histiocytosis with braf v600e mutation |
| topic | BRAF protein congenital self‐healing Langerhans cell histiocytosis histiocytosis Langerhans cell histiocytosis mitogen‐activated protein kinases (MAPKs) |
| url | https://doi.org/10.1002/jvc2.14 |
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