Characterization and Immunogenicity of HIV Envelope gp140 Zera® Tagged Antigens

Characterization and Immunogenicity of HIV Envelope gp140 Zera® Tagged Antigens

HIV-1 envelope glycoprotein (Env) remains the most relevant target for the elicitation of functional antibodies to HIV by vaccination. However, soluble Env antigens often do not elicit the desired immune responses. Delivering subunit antigens on particulate nanoparticles is an established approach t...

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Bibliographic Details
Main Authors: Phindile Ximba, Rosamund Chapman, Ann E. Meyers, Emmanuel Margolin, Michiel T. van Diepen, Anna-Lise Williamson, Edward P. Rybicki
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
HIV-1
protein body
envelope protein
vaccine
Zera®
immunogenicity
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00321/full

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