Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination
Abstract Background Participation in epidemiological studies has strongly declined in recent years. We examined the reasons for (non)participation in population-based health studies among participants and nonparticipants of a prospective study on influenza vaccination among the elderly. Methods Male...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2017-02-01
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| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12874-017-0302-z |
| _version_ | 1818153699659218944 |
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| author | Manas K. Akmatov Leonhard Jentsch Peggy Riese Marcus May Malik W. Ahmed Damaris Werner Anja Rösel Jana Prokein Inga Bernemann Norman Klopp Blair Prochnow Thomas Illig Christoph Schindler Carlos A. Guzman Frank Pessler |
| author_facet | Manas K. Akmatov Leonhard Jentsch Peggy Riese Marcus May Malik W. Ahmed Damaris Werner Anja Rösel Jana Prokein Inga Bernemann Norman Klopp Blair Prochnow Thomas Illig Christoph Schindler Carlos A. Guzman Frank Pessler |
| author_sort | Manas K. Akmatov |
| collection | DOAJ |
| description | Abstract Background Participation in epidemiological studies has strongly declined in recent years. We examined the reasons for (non)participation in population-based health studies among participants and nonparticipants of a prospective study on influenza vaccination among the elderly. Methods Males and females between 65 and 80 years of age (N = 5582) were randomly selected from the residents’ registration office in Hannover, Germany, and were invited to participate in a study featuring vaccination with a seasonal adjuvanted influenza vaccine (Fluad™, Novartis) including five follow-up visits (day 0, 1/3, 7, 21, 70 with respect to vaccination). A 24-item nonresponder questionnaire, including 10 items on reasons for participating in a hypothetical health study, was mailed to 1500 randomly selected nonparticipants. The same 10 items were included in the end-of-study questionnaire administered to the participants in the vaccination study (n = 200). Logistic regression analysis with backward elimination was used to identify the reasons most strongly associated with nonparticipation. Results Five hundred thirty-one (35%) nonparticipants and 200 participants (100%) returned the respective questionnaires. Nonparticipation was associated with a lower interest in obtaining personal health information (OR = 3.32) and a preference for less invasive (OR = 3.01) and less time-demanding (OR = 2.19) studies. Responses to other items, e.g. regarding altruistic motives, monetary compensation, general interest of the study, or study approval through ethics committee and data security authority, did not differ between participants and nonparticipants. Conclusions Participation rates in health studies among elderly individuals could potentially be improved by reducing interventions and time demand, for instance by implementing methods of self-sampling and remote data collection. Trial registration No. 1100359 (ClinicalTrials.gov, date of registration: 09.02.2015). |
| first_indexed | 2024-12-11T14:14:46Z |
| format | Article |
| id | doaj.art-d86fc655d2024b3ea66edade055a8a34 |
| institution | Directory Open Access Journal |
| issn | 1471-2288 |
| language | English |
| last_indexed | 2024-12-11T14:14:46Z |
| publishDate | 2017-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Research Methodology |
| spelling | doaj.art-d86fc655d2024b3ea66edade055a8a342022-12-22T01:03:14ZengBMCBMC Medical Research Methodology1471-22882017-02-011711910.1186/s12874-017-0302-zMotivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccinationManas K. Akmatov0Leonhard Jentsch1Peggy Riese2Marcus May3Malik W. Ahmed4Damaris Werner5Anja Rösel6Jana Prokein7Inga Bernemann8Norman Klopp9Blair Prochnow10Thomas Illig11Christoph Schindler12Carlos A. Guzman13Frank Pessler14TWINCORE, Centre for Experimental and Clinical Infection ResearchTWINCORE, Centre for Experimental and Clinical Infection ResearchHelmholtz Centre for Infection ResearchMHH CRC Core Facility, Hannover Medical SchoolTWINCORE, Centre for Experimental and Clinical Infection ResearchTWINCORE, Centre for Experimental and Clinical Infection ResearchTWINCORE, Centre for Experimental and Clinical Infection ResearchHannover Unified Biobank, Hannover Medical SchoolHannover Unified Biobank, Hannover Medical SchoolHannover Unified Biobank, Hannover Medical SchoolHelmholtz Centre for Infection ResearchHannover Unified Biobank, Hannover Medical SchoolMHH CRC Core Facility, Hannover Medical SchoolHelmholtz Centre for Infection ResearchTWINCORE, Centre for Experimental and Clinical Infection ResearchAbstract Background Participation in epidemiological studies has strongly declined in recent years. We examined the reasons for (non)participation in population-based health studies among participants and nonparticipants of a prospective study on influenza vaccination among the elderly. Methods Males and females between 65 and 80 years of age (N = 5582) were randomly selected from the residents’ registration office in Hannover, Germany, and were invited to participate in a study featuring vaccination with a seasonal adjuvanted influenza vaccine (Fluad™, Novartis) including five follow-up visits (day 0, 1/3, 7, 21, 70 with respect to vaccination). A 24-item nonresponder questionnaire, including 10 items on reasons for participating in a hypothetical health study, was mailed to 1500 randomly selected nonparticipants. The same 10 items were included in the end-of-study questionnaire administered to the participants in the vaccination study (n = 200). Logistic regression analysis with backward elimination was used to identify the reasons most strongly associated with nonparticipation. Results Five hundred thirty-one (35%) nonparticipants and 200 participants (100%) returned the respective questionnaires. Nonparticipation was associated with a lower interest in obtaining personal health information (OR = 3.32) and a preference for less invasive (OR = 3.01) and less time-demanding (OR = 2.19) studies. Responses to other items, e.g. regarding altruistic motives, monetary compensation, general interest of the study, or study approval through ethics committee and data security authority, did not differ between participants and nonparticipants. Conclusions Participation rates in health studies among elderly individuals could potentially be improved by reducing interventions and time demand, for instance by implementing methods of self-sampling and remote data collection. Trial registration No. 1100359 (ClinicalTrials.gov, date of registration: 09.02.2015).http://link.springer.com/article/10.1186/s12874-017-0302-zParticipationNonparticipantsReasonsMotivationsPopulation-based studyElderly |
| spellingShingle | Manas K. Akmatov Leonhard Jentsch Peggy Riese Marcus May Malik W. Ahmed Damaris Werner Anja Rösel Jana Prokein Inga Bernemann Norman Klopp Blair Prochnow Thomas Illig Christoph Schindler Carlos A. Guzman Frank Pessler Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination BMC Medical Research Methodology Participation Nonparticipants Reasons Motivations Population-based study Elderly |
| title | Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination |
| title_full | Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination |
| title_fullStr | Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination |
| title_full_unstemmed | Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination |
| title_short | Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination |
| title_sort | motivations for non participation in population based health studies among the elderly comparison of participants and nonparticipants of a prospective study on influenza vaccination |
| topic | Participation Nonparticipants Reasons Motivations Population-based study Elderly |
| url | http://link.springer.com/article/10.1186/s12874-017-0302-z |
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