VIPoma Crisis : Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide
We report the case of a 57-year-old male physician who presented with a life threatening secretory and refractory diarrhoea of around 20 L/day. This was complicated by severe hypotension, hypokalaemia, hypercalcaemia, renal failure requiring dialysis, metabolic acidosis, cardiorespiratory arrest and...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sultan Qaboos University
2011-04-01
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| Series: | Sultan Qaboos University Medical Journal |
| Subjects: | |
| Online Access: | https://journals.squ.edu.om/index.php/squmj/article/view/1553 |
| _version_ | 1818643188510883840 |
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| author | Omayma ElShafie Christopher Grant Aisha Al-Hamdani Rajeev Jain Nicholas Woodhouse |
| author_facet | Omayma ElShafie Christopher Grant Aisha Al-Hamdani Rajeev Jain Nicholas Woodhouse |
| author_sort | Omayma ElShafie |
| collection | DOAJ |
| description | We report the case of a 57-year-old male physician who presented with a life threatening secretory and refractory diarrhoea of around 20 L/day. This was complicated by severe hypotension, hypokalaemia, hypercalcaemia, renal failure requiring dialysis, metabolic acidosis, cardiorespiratory arrest and ventilation for 12 days. His diarrhoea responded immediately to the first dose of a therapeutic trial of subcutaneous octreotide 100 mcg 8 hourly which was started on clinical grounds alone before any investigations were carried out. After one day he was extubated and his blood pressure returned to normal. When a functioning neuroendocrine tumour is suspected clinically, the use of octreotide can, as in this case, be life saving. |
| first_indexed | 2024-12-16T23:54:59Z |
| format | Article |
| id | doaj.art-d872aec35f254b348ab2e875ad232de0 |
| institution | Directory Open Access Journal |
| issn | 2075-051X 2075-0528 |
| language | English |
| last_indexed | 2024-12-16T23:54:59Z |
| publishDate | 2011-04-01 |
| publisher | Sultan Qaboos University |
| record_format | Article |
| series | Sultan Qaboos University Medical Journal |
| spelling | doaj.art-d872aec35f254b348ab2e875ad232de02022-12-21T22:11:13ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282011-04-011111041071479VIPoma Crisis : Immediate and life saving reduction of massive stool volumes on starting treatment with octreotideOmayma ElShafie0Christopher Grant1Aisha Al-Hamdani2Rajeev Jain3Nicholas Woodhouse4Departments of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.Departments of Surgerye, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.Departments of Pathology Sultan Qaboos University Hospital, Muscat, OmanDepartments of Radiology & Molecular Imaging, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.Departments Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.We report the case of a 57-year-old male physician who presented with a life threatening secretory and refractory diarrhoea of around 20 L/day. This was complicated by severe hypotension, hypokalaemia, hypercalcaemia, renal failure requiring dialysis, metabolic acidosis, cardiorespiratory arrest and ventilation for 12 days. His diarrhoea responded immediately to the first dose of a therapeutic trial of subcutaneous octreotide 100 mcg 8 hourly which was started on clinical grounds alone before any investigations were carried out. After one day he was extubated and his blood pressure returned to normal. When a functioning neuroendocrine tumour is suspected clinically, the use of octreotide can, as in this case, be life saving.https://journals.squ.edu.om/index.php/squmj/article/view/1553vipomadiarrhoeapancreatic tumourneuroendocrine tumouroctreotidechromogranin acardiopulmonary arrestcase reportoman |
| spellingShingle | Omayma ElShafie Christopher Grant Aisha Al-Hamdani Rajeev Jain Nicholas Woodhouse VIPoma Crisis : Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide Sultan Qaboos University Medical Journal vipoma diarrhoea pancreatic tumour neuroendocrine tumour octreotide chromogranin a cardiopulmonary arrest case report oman |
| title | VIPoma Crisis : Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide |
| title_full | VIPoma Crisis : Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide |
| title_fullStr | VIPoma Crisis : Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide |
| title_full_unstemmed | VIPoma Crisis : Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide |
| title_short | VIPoma Crisis : Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide |
| title_sort | vipoma crisis immediate and life saving reduction of massive stool volumes on starting treatment with octreotide |
| topic | vipoma diarrhoea pancreatic tumour neuroendocrine tumour octreotide chromogranin a cardiopulmonary arrest case report oman |
| url | https://journals.squ.edu.om/index.php/squmj/article/view/1553 |
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