PD1 Deficiency Modifies Cardiac Immunity during Baseline Conditions and in Reperfused Acute Myocardial Infarction

PD1 Deficiency Modifies Cardiac Immunity during Baseline Conditions and in Reperfused Acute Myocardial Infarction

The programmed cell death protein 1 (PD1) immune checkpoint prevents inflammatory tissue damage by inhibiting immune reactions. Understanding the relevance of cardiac PD1 signaling may provide new insights into the inflammatory events under baseline conditions and disease. Here, we demonstrate disti...

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Bibliographic Details
Main Authors: Lars Michel, Sebastian Korste, Armin Spomer, Ulrike Barbara Hendgen-Cotta, Tienush Rassaf, Matthias Totzeck
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
cardio-oncology
immune checkpoint
immunology
ischemia/reperfusion injury
reperfused acute myocardial infarction
programmed cell death protein 1
Online Access:https://www.mdpi.com/1422-0067/23/14/7533

Internet

https://www.mdpi.com/1422-0067/23/14/7533

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