Transcriptional and apoptotic responses of THP-1 cells to challenge with toxigenic, and non-toxigenic <it>Bacillus anthracis</it>

Transcriptional and apoptotic responses of THP-1 cells to challenge with toxigenic, and non-toxigenic <it>Bacillus anthracis</it>

<p>Abstract</p> <p>Background</p> <p><it>Bacillus anthracis </it>secretes several virulence factors targeting different host organs and cell types during inhalational anthrax infection. The bacterial expression of a key virulence factor, lethal toxin (LeTx)...

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Bibliographic Details
Main Authors: Bailey Charles, Popova Anna, Popova Taissia, Liu Derong, Schlauch Karen, Zong Qin, Chung Myung-Chul, Bradburne Christopher, Soppet Dan, Popov Serguei
Format: Article
Language:English
Published: BMC 2008-11-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/9/67

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