PTEN gene mutations in malignant tumours – a systematic review and clinical implications for tumour treatment

PTEN gene mutations in malignant tumours – a systematic review and clinical implications for tumour treatment

Bibliographic Details
Main Authors:	Magdalena Kołomańska, Łukasz Nawacki, Łukasz Madej, Jarosław Matykiewicz, Aldona Kubala-Kukuś, Stanisław Głuszek
Format:	Article
Language:	English
Published:	Termedia Publishing House 2022-12-01
Series:	Studia Medyczne
Subjects:	carcinogenesis pten mutation mmac-1 mutation tep-1 mutation cancer genetics
Online Access:	https://www.termedia.pl/PTEN-gene-mutations-in-malignant-tumours-a-systematic-review-and-clinical-implications-for-tumour-treatment,67,48727,1,1.html

Similar Items

TP53 and PTEN as driver mutations in Zenker's carcinoma—a clinical presentation
by: Zsanett Noel, et al.
Published: (2020-12-01)

Clinical Phenotype and Immunological Characteristics of A Patient with De Novo Heterozygous Mutation of PTEN
by: QIU Luyao, et al.
Published: (2023-03-01)

Premalignant alterations in breast and endometrium associated with a PTEN mutation in a woman with Cowden syndrome: implications for preventive care
by: Christopher B. Morse, et al.
Published: (2015-04-01)

New PTEN mutation identified in a patient with rare bilateral choroidal ganglioneuroma
by: Zhaoxin Jiang, et al.
Published: (2020-12-01)

Functions and regulation of the PTEN gene in colorectal cancer
by: Francesca eMolinari, et al.
Published: (2014-01-01)

Prevalence and clinical/molecular characteristics of PTEN mutations in Turkish children with autism spectrum disorders and macrocephaly
by: Hande Kaymakcalan, et al.
Published: (2021-08-01)

Case Report: PTEN Mutation Induced by anti-PD-1 Therapy in Stage IV Lung Adenocarcinoma
by: Junjie Teng, et al.
Published: (2022-05-01)

Sirolimus treatment of a PTEN hamartoma tumor syndrome presenting with melena
by: Gülseren Evirgen Şahin, et al.
Published: (2022-08-01)

Erratum: Case report: PTEN mutation induced by anti-PD-1 therapy in stage IV lung adenocarcinoma
by: Frontiers Production Office
Published: (2022-10-01)

Influence of PTEN mutation on pathological features and prognosis of patients with mucosal melanoma
by: GONG Ziqi, WU Xiaowen, GUO Qian, GUO Jun, KONG Yan
Published: (2023-09-01)

Distinguishing between PTEN clinical phenotypes through mutation analysis
by: Stephanie Portelli, et al.
Published: (2021-01-01)

Neurofibromatosis type 1-associated tumours: Their somatic mutational spectrum and pathogenesis
by: Spyk Sebastian, et al.
Published: (2011-10-01)

Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis
by: Jian Sun, et al.
Published: (2019-12-01)

Predictors of Multiple Primary Malignancies: Literature Review
by: A. V. Sultanbaev, et al.
Published: (2023-10-01)

PTEN Mutation Related Unilateral Multicentric, Synchronous and Metachronous Bilateral Breast Cancer: Three Case Reports
by: YAO Ru, et al.
Published: (2024-07-01)

Case report: Rare oral manifestations in Cowden syndrome with PTEN mutation
by: Wei Yuan, et al.
Published: (2024-02-01)

Understanding carcinogenesis : an introduction to the molecular basis of cancer /
by: 183880 Kiaris, Hippokratis
Published: (2006)

Review of cancer from perspective of molecular
by: Seyed Hossein Hassanpour, et al.
Published: (2017-12-01)

Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation
by: Yan Xing, et al.
Published: (2019-07-01)

Effect of PTEN Gene Mutations and Environmental Risk Factors on the Progression and Prognosis of Bladder Cancer.
by: Rahil Mashhadi, et al.
Published: (2014-01-01)

Emergent properties of a computational model of tumour growth
by: Pan Pantziarka
Published: (2016-06-01)

Lactic Acidosis in Prostate Cancer: Consider the Warburg Effect
by: Johannes C. van der Mijn, et al.
Published: (2017-11-01)

Tp53 Mutation Inhibits Ubiquitination and Degradation of WISP1 via Down-Regulation of Siah1 in Pancreatic Carcinogenesis
by: Wei Wu, et al.
Published: (2018-08-01)

Advances in the treatment of advanced melanoma with NRAS gene mutation
by: ZHAO Bolun, ZHU Guannan
Published: (2023-10-01)

Genomic clustering of fitness‐affecting mutations favors the evolution of chromosomal instability
by: Yevgeniy Raynes, et al.
Published: (2019-02-01)

<title language="eng">Carcinogénesis
by: María Teresa Martín de Civetta, et al.
Published: (2011-10-01)

PTEN-related risk classification models for predicting prognosis and immunotherapy response of hepatocellular carcinoma
by: Lu Cao, et al.
Published: (2023-07-01)

Hereditary breast cancer associated with Cowden syndrome-related PTEN mutation with Lhermitte-Duclos disease
by: Fuyo Kimura, et al.
Published: (2017-07-01)

Novel compounds that synergize with aminoglycoside G418 or eRF3 degraders for translational readthrough of nonsense mutant TP53 and PTEN
by: Angelos Heldin, et al.
Published: (2023-12-01)

Significance of PTEN Mutation in Cellular Process, Prognosis, and Drug Selection in Clear Cell Renal Cell Carcinoma
by: Caibin Fan, et al.
Published: (2019-05-01)

Rapid Mutation Scanning of Genes Associated with Familial Cancer Syndromes Using Denaturing High-Performance Liquid Chromatography
by: Deborah J. Marsh, et al.
Published: (2001-01-01)

Molecular landscape of borderline ovarian tumours: A systematic review
by: Sadlecki Pawel, et al.
Published: (2024-06-01)

The role of mutation in the new cancer paradigm
by: Prehn Richmond T
Published: (2005-04-01)

Mitochondrial changes in carcinogenesis as a goal of antitumor therapy (review)
by: T. E. Potemina, et al.
Published: (2020-12-01)

Origin of cancer: an information, energy and matter disease
by: Rainer Günter Hanselmann, et al.
Published: (2016-11-01)

Connection between tumor suppressor BRCA1 and PTEN in damaged DNA repair
by: Akari eMinami, et al.
Published: (2014-11-01)

Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity
by: Nick Sarn, et al.
Published: (2021-06-01)

High Prevalence of Mitochondrial tRNA A3243G Mutation in Invasive Breast Cancer
by: Mohammed A. Alhomidi, et al.
Published: (2021-06-01)

ANALYSIS OF TP53, APC, KRAS, AND MMR GENETIC MUTATIONS IN COLORECTAL CANCER: A REVIEW ARTICLE
by: Gavric Igor, et al.
Published: (2024-12-01)

A probabilistic method for leveraging functional annotations to enhance estimation of the temporal order of pathway mutations during carcinogenesis
by: Menghan Wang, et al.
Published: (2019-12-01)