N-acetyl-L-leucine protects MPTP-treated Parkinson’s disease mouse models by suppressing Desulfobacterota via the gut-brain axis

N-acetyl-L-leucine protects MPTP-treated Parkinson’s disease mouse models by suppressing Desulfobacterota via the gut-brain axis

Parkinson's disease (PD) is the second most common neurodegenerative disease, and communication between the gut and brain (the gut-brain axis) has been found to be essential in behavior and cognitive function. However, the exact mechanisms underlying microbiota dysbiosis in PD progression have...

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Bibliographic Details
Main Authors: Zhifeng Xu, Changlin Lian, Lixin Pan, Wenjie Lai, Fen Zhang, Lingmei Peng, Sijie Zhou, Guanghua Zhao, Xuezhu Yang, Guohua Zhang, Zefeng Tan, Yukai Wang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Brain Research Bulletin
Subjects:
Desulfobacterota
Microbiota dysbiosis
Gut-brain axis
N-acetyl-L-leucine
Parkinson’s disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023001545

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http://www.sciencedirect.com/science/article/pii/S0361923023001545

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