The Functional Role of Myogenin in Cardiomyoblast H9c2 Cells Treated with High Glucose and Palmitic Acid: Insights into No-Rejection Heart Transplantation

The Functional Role of Myogenin in Cardiomyoblast H9c2 Cells Treated with High Glucose and Palmitic Acid: Insights into No-Rejection Heart Transplantation

Various pathological alterations, including lipid-deposition-induced comparative cardiac lipotoxicity, contribute to cardiac aging in the failing heart. A decline in endogenous myogenin proteins can lead to the reversal of muscle cell differentiation and the creation of mononucleated muscle cells. M...

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Bibliographic Details
Main Authors: Po-Shun Hsu, Shu-Ting Liu, Yi-Lin Chiu, Chien-Sung Tsai
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
myogenin
palmitic acid
cell differentiation
reactive oxygen species
transplantation
Online Access:https://www.mdpi.com/1422-0067/24/17/13031

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