Epidemiology of Helicobacter pylori in Australia: a scoping review
Background Helicobacter pylori (H. pylori), a bacterium implicated in the development of peptic ulcer and gastric cancer, is estimated to infect around half the world’s population. Its prevalence in Australia is unclear. This scoping review aimed to evaluate all Australian literature providing estim...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2022-05-01
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| Online Access: | https://peerj.com/articles/13430.pdf |
| _version_ | 1797419037949427712 |
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| author | Jillian Congedi Craig Williams Katherine L. Baldock |
| author_facet | Jillian Congedi Craig Williams Katherine L. Baldock |
| author_sort | Jillian Congedi |
| collection | DOAJ |
| description | Background Helicobacter pylori (H. pylori), a bacterium implicated in the development of peptic ulcer and gastric cancer, is estimated to infect around half the world’s population. Its prevalence in Australia is unclear. This scoping review aimed to evaluate all Australian literature providing estimates of the prevalence of H. pylori. Methods Australian studies examining H. pylori prevalence from 1982 onwards were eligible for inclusion. Medline, Embase and Scopus databases, and grey literature sources, were searched. Two independent reviewers undertook a two-stage screening process. Data were extracted by two independent reviewers using a pre-specified template. Results Of 444 identified studies, 75 were included in the review. H. pylori prevalence in Australian population-based studies (n = 8) ranged from 38.0% in 1991 to 15.1% in 2002; however, estimated prevalence across all non-clinical population studies in diverse sub-groups (n = 29) has varied dramatically. Decreased prevalence has been more marked in populations with gastrointestinal symptoms and conditions compared to non-clinical populations. Data on H. pyloriprevalence in vulnerable populations are lacking. Conclusions This is the first scoping review of Australian studies reporting H. pylori prevalence. A wide range of study designs, population groups, geographic regions, and diagnostic methods was included, involving data collected over a 50-year period (1969 to 2018). The summary of H. pylori prevalence estimates over time in this review points to a decrease in prevalence in Australia, particularly among populations with gastrointestinal symptoms and illnesses; however, it is unknown whether there is inequity in prevalence trends across vulnerable sub-groups of the Australian population. Future research and interventions supporting the health and wellbeing of vulnerable populations is required to ensure equitable health gains are made for all. |
| first_indexed | 2024-03-09T06:41:46Z |
| format | Article |
| id | doaj.art-d87e65fd0e434cd490821e93235472cc |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T06:41:46Z |
| publishDate | 2022-05-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
| series | PeerJ |
| spelling | doaj.art-d87e65fd0e434cd490821e93235472cc2023-12-03T10:49:44ZengPeerJ Inc.PeerJ2167-83592022-05-0110e1343010.7717/peerj.13430Epidemiology of Helicobacter pylori in Australia: a scoping reviewJillian Congedi0Craig Williams1Katherine L. Baldock2UniSA Allied Health and Human Performance, Australian Centre for Precision Health, University of South Australia, Adelaide, South Australia, AustraliaUniSA Clinical and Health Sciences, Australian Centre for Precision Health, University of South Australia, Adelaide, South Australia, AustraliaUniSA Allied Health and Human Performance, Australian Centre for Precision Health, University of South Australia, Adelaide, South Australia, AustraliaBackground Helicobacter pylori (H. pylori), a bacterium implicated in the development of peptic ulcer and gastric cancer, is estimated to infect around half the world’s population. Its prevalence in Australia is unclear. This scoping review aimed to evaluate all Australian literature providing estimates of the prevalence of H. pylori. Methods Australian studies examining H. pylori prevalence from 1982 onwards were eligible for inclusion. Medline, Embase and Scopus databases, and grey literature sources, were searched. Two independent reviewers undertook a two-stage screening process. Data were extracted by two independent reviewers using a pre-specified template. Results Of 444 identified studies, 75 were included in the review. H. pylori prevalence in Australian population-based studies (n = 8) ranged from 38.0% in 1991 to 15.1% in 2002; however, estimated prevalence across all non-clinical population studies in diverse sub-groups (n = 29) has varied dramatically. Decreased prevalence has been more marked in populations with gastrointestinal symptoms and conditions compared to non-clinical populations. Data on H. pyloriprevalence in vulnerable populations are lacking. Conclusions This is the first scoping review of Australian studies reporting H. pylori prevalence. A wide range of study designs, population groups, geographic regions, and diagnostic methods was included, involving data collected over a 50-year period (1969 to 2018). The summary of H. pylori prevalence estimates over time in this review points to a decrease in prevalence in Australia, particularly among populations with gastrointestinal symptoms and illnesses; however, it is unknown whether there is inequity in prevalence trends across vulnerable sub-groups of the Australian population. Future research and interventions supporting the health and wellbeing of vulnerable populations is required to ensure equitable health gains are made for all.https://peerj.com/articles/13430.pdfHelicobacter pyloriEpidemiologyPrevalenceAustraliaScoping review |
| spellingShingle | Jillian Congedi Craig Williams Katherine L. Baldock Epidemiology of Helicobacter pylori in Australia: a scoping review PeerJ Helicobacter pylori Epidemiology Prevalence Australia Scoping review |
| title | Epidemiology of Helicobacter pylori in Australia: a scoping review |
| title_full | Epidemiology of Helicobacter pylori in Australia: a scoping review |
| title_fullStr | Epidemiology of Helicobacter pylori in Australia: a scoping review |
| title_full_unstemmed | Epidemiology of Helicobacter pylori in Australia: a scoping review |
| title_short | Epidemiology of Helicobacter pylori in Australia: a scoping review |
| title_sort | epidemiology of helicobacter pylori in australia a scoping review |
| topic | Helicobacter pylori Epidemiology Prevalence Australia Scoping review |
| url | https://peerj.com/articles/13430.pdf |
| work_keys_str_mv | AT jilliancongedi epidemiologyofhelicobacterpyloriinaustraliaascopingreview AT craigwilliams epidemiologyofhelicobacterpyloriinaustraliaascopingreview AT katherinelbaldock epidemiologyofhelicobacterpyloriinaustraliaascopingreview |