Se-Methylselenocysteine Inhibits Apoptosis Induced by Clusterin Knockdown in Neuroblastoma N2a and SH-SY5Y Cell Lines

Se-Methylselenocysteine Inhibits Apoptosis Induced by Clusterin Knockdown in Neuroblastoma N2a and SH-SY5Y Cell Lines

Apoptosis, as a programmed cell death process, is essential for the maintenance of tissue function in organisms. Alteration of this process is linked to many diseases. Over-expression of clusterin (Clu) can antagonize apoptosis in various cells. Selenium (Se) is an essential trace element for human...

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Bibliographic Details
Main Authors: Chao Wang, Zhenyu Zeng, Qiong Liu, Renli Zhang, Jiazuan Ni
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:International Journal of Molecular Sciences
Subjects:
clusterin (Clu)
Se-methylselenocysteine (MSC)
cell apoptosis
RNA interference (RNAi)
gene knockdown
Online Access:http://www.mdpi.com/1422-0067/15/11/21331

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