Possible Association between Glucose-6-Phosphate Dehydrogenase Deficiency and the Development of Preeclampsia

Glucose-6-Phosphate dehydrogenase (G6PD) deficiency is acommon enzyme deficiency in the world. It's Prevalence inIran is about 12% in male & about 1% in female. The presentstudy did examine the relation between the development ofpreeclampsia and G6PD deficiency. It was investigatedwhether o...

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Main Authors: Omid R. Zekavat, Maryam Eskandary, Behia Namavar Jahromi, Athar Rasekh, Sara Barzegar, Nasrin Ized Panahy, Mehran Karimi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2010-12-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:http://ijms.sums.ac.ir/files/PDFfiles/10-Dr_%20Karimi.pdf
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author Omid R. Zekavat
Maryam Eskandary
Behia Namavar Jahromi
Athar Rasekh
Sara Barzegar
Nasrin Ized Panahy
Mehran Karimi
author_facet Omid R. Zekavat
Maryam Eskandary
Behia Namavar Jahromi
Athar Rasekh
Sara Barzegar
Nasrin Ized Panahy
Mehran Karimi
author_sort Omid R. Zekavat
collection DOAJ
description Glucose-6-Phosphate dehydrogenase (G6PD) deficiency is acommon enzyme deficiency in the world. It's Prevalence inIran is about 12% in male & about 1% in female. The presentstudy did examine the relation between the development ofpreeclampsia and G6PD deficiency. It was investigatedwhether or not the risk of preeclampsia in G6PD deficientwomen is higher than that in normal pregnant women.A total of 400 pregnant patients with an age range of 20-34years were selected in the cities of Shiraz and Jahrom, Iran,They were on 24 weeks inside their first or second pregnancy.There were 4 cases of G6PD deficiency in preeclamtic womencompared to two cases in normal pregnant women. (OR=2.02,CI: 0.37-11.02). Although the relation between G6PD deficiencyand preeclamsia did not reach statistical significance,the higher incidence of the deficiency in preecclamtic womenmight suggest that the test for G6PD deficiency might be usedas a screening tool for preeclamsia.Iran J Med Sci 2010; 35(4): 323-326.
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spelling doaj.art-d8828c870dfe4aaea9da96a9b12141a12022-12-22T00:07:09ZengShiraz University of Medical SciencesIranian Journal of Medical Sciences0253-07161735-36882010-12-01354323326Possible Association between Glucose-6-Phosphate Dehydrogenase Deficiency and the Development of PreeclampsiaOmid R. ZekavatMaryam EskandaryBehia Namavar JahromiAthar RasekhSara BarzegarNasrin Ized PanahyMehran KarimiGlucose-6-Phosphate dehydrogenase (G6PD) deficiency is acommon enzyme deficiency in the world. It's Prevalence inIran is about 12% in male & about 1% in female. The presentstudy did examine the relation between the development ofpreeclampsia and G6PD deficiency. It was investigatedwhether or not the risk of preeclampsia in G6PD deficientwomen is higher than that in normal pregnant women.A total of 400 pregnant patients with an age range of 20-34years were selected in the cities of Shiraz and Jahrom, Iran,They were on 24 weeks inside their first or second pregnancy.There were 4 cases of G6PD deficiency in preeclamtic womencompared to two cases in normal pregnant women. (OR=2.02,CI: 0.37-11.02). Although the relation between G6PD deficiencyand preeclamsia did not reach statistical significance,the higher incidence of the deficiency in preecclamtic womenmight suggest that the test for G6PD deficiency might be usedas a screening tool for preeclamsia.Iran J Med Sci 2010; 35(4): 323-326.http://ijms.sums.ac.ir/files/PDFfiles/10-Dr_%20Karimi.pdfG6PD deficiencypreeclampsiapregnancy
spellingShingle Omid R. Zekavat
Maryam Eskandary
Behia Namavar Jahromi
Athar Rasekh
Sara Barzegar
Nasrin Ized Panahy
Mehran Karimi
Possible Association between Glucose-6-Phosphate Dehydrogenase Deficiency and the Development of Preeclampsia
Iranian Journal of Medical Sciences
G6PD deficiency
preeclampsia
pregnancy
title Possible Association between Glucose-6-Phosphate Dehydrogenase Deficiency and the Development of Preeclampsia
title_full Possible Association between Glucose-6-Phosphate Dehydrogenase Deficiency and the Development of Preeclampsia
title_fullStr Possible Association between Glucose-6-Phosphate Dehydrogenase Deficiency and the Development of Preeclampsia
title_full_unstemmed Possible Association between Glucose-6-Phosphate Dehydrogenase Deficiency and the Development of Preeclampsia
title_short Possible Association between Glucose-6-Phosphate Dehydrogenase Deficiency and the Development of Preeclampsia
title_sort possible association between glucose 6 phosphate dehydrogenase deficiency and the development of preeclampsia
topic G6PD deficiency
preeclampsia
pregnancy
url http://ijms.sums.ac.ir/files/PDFfiles/10-Dr_%20Karimi.pdf
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AT behianamavarjahromi possibleassociationbetweenglucose6phosphatedehydrogenasedeficiencyandthedevelopmentofpreeclampsia
AT atharrasekh possibleassociationbetweenglucose6phosphatedehydrogenasedeficiencyandthedevelopmentofpreeclampsia
AT sarabarzegar possibleassociationbetweenglucose6phosphatedehydrogenasedeficiencyandthedevelopmentofpreeclampsia
AT nasrinizedpanahy possibleassociationbetweenglucose6phosphatedehydrogenasedeficiencyandthedevelopmentofpreeclampsia
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