Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody

Here, the authors present a noninvasive tool to detect liver inflammation using nuclear imaging, as an alternative to biopsy. The prove the diagnostic power of this tool to detect liver inflammation in preclinical models of chronic liver disease.

Bibliographic Details
Main Authors: Maxime Nachit, Christopher Montemagno, Romain Clerc, Mitra Ahmadi, François Briand, Sandrine Bacot, Nick Devoogdt, Cindy Serdjebi, Catherine Ghezzi, Thierry Sulpice, Alexis Broisat, Isabelle A. Leclercq, Pascale Perret
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36776-7
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author Maxime Nachit
Christopher Montemagno
Romain Clerc
Mitra Ahmadi
François Briand
Sandrine Bacot
Nick Devoogdt
Cindy Serdjebi
Catherine Ghezzi
Thierry Sulpice
Alexis Broisat
Isabelle A. Leclercq
Pascale Perret
author_facet Maxime Nachit
Christopher Montemagno
Romain Clerc
Mitra Ahmadi
François Briand
Sandrine Bacot
Nick Devoogdt
Cindy Serdjebi
Catherine Ghezzi
Thierry Sulpice
Alexis Broisat
Isabelle A. Leclercq
Pascale Perret
author_sort Maxime Nachit
collection DOAJ
description Here, the authors present a noninvasive tool to detect liver inflammation using nuclear imaging, as an alternative to biopsy. The prove the diagnostic power of this tool to detect liver inflammation in preclinical models of chronic liver disease.
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spelling doaj.art-d88758d761954f49a5f4a5060910e50c2023-03-22T11:43:02ZengNature PortfolioNature Communications2041-17232023-02-0114111210.1038/s41467-023-36776-7Molecular imaging of liver inflammation using an anti-VCAM-1 nanobodyMaxime Nachit0Christopher Montemagno1Romain Clerc2Mitra Ahmadi3François Briand4Sandrine Bacot5Nick Devoogdt6Cindy Serdjebi7Catherine Ghezzi8Thierry Sulpice9Alexis Broisat10Isabelle A. Leclercq11Pascale Perret12Laboratory of Hepato-Gastroenterology, Institut de Recherche Expérimentale et Clinique, UCLouvainUniv. Grenoble Alpes, INSERM, LRBUniv. Grenoble Alpes, INSERM, LRBUniv. Grenoble Alpes, INSERM, LRBPhysiogenexUniv. Grenoble Alpes, INSERM, LRBDepartment of Medical Imaging, Laboratory of in vivo Cellular and Molecular Imaging, Vrije Universiteit BrusselBiocellviaUniv. Grenoble Alpes, INSERM, LRBPhysiogenexUniv. Grenoble Alpes, INSERM, LRBLaboratory of Hepato-Gastroenterology, Institut de Recherche Expérimentale et Clinique, UCLouvainUniv. Grenoble Alpes, INSERM, LRBHere, the authors present a noninvasive tool to detect liver inflammation using nuclear imaging, as an alternative to biopsy. The prove the diagnostic power of this tool to detect liver inflammation in preclinical models of chronic liver disease.https://doi.org/10.1038/s41467-023-36776-7
spellingShingle Maxime Nachit
Christopher Montemagno
Romain Clerc
Mitra Ahmadi
François Briand
Sandrine Bacot
Nick Devoogdt
Cindy Serdjebi
Catherine Ghezzi
Thierry Sulpice
Alexis Broisat
Isabelle A. Leclercq
Pascale Perret
Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody
Nature Communications
title Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody
title_full Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody
title_fullStr Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody
title_full_unstemmed Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody
title_short Molecular imaging of liver inflammation using an anti-VCAM-1 nanobody
title_sort molecular imaging of liver inflammation using an anti vcam 1 nanobody
url https://doi.org/10.1038/s41467-023-36776-7
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