A periosteum-derived cell line to study the role of BMP/TGFβ signaling in periosteal cell behavior and function

A periosteum-derived cell line to study the role of BMP/TGFβ signaling in periosteal cell behavior and function

The periosteum is a thin tissue surrounding each skeletal element that contains stem and progenitor cells involved in bone development, postnatal appositional bone growth, load-induced bone formation, and fracture repair. BMP and TGFβ signaling are important for periosteal activity and periosteal ce...

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Bibliographic Details
Main Authors: Emily R. Moore, David E. Maridas, Laura Gamer, Gavin Chen, Kathryn Burton, Vicki Rosen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Physiology
Subjects:
periosteum
cell line
BMP signaling
TGFβ signaling
mechanotransduction
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1221152/full

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