Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide
Crystal structures of methyl 2-pentyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide 1 and methyl 2-pentenyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide 2 have been determined after their synthesis from saccharin. 1 and 2 crystallize in a monoclinic and orthorhombic crystal sy...
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| Format: | Article |
| Language: | English |
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Walailak University
2012-03-01
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| Series: | Walailak Journal of Science and Technology |
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| Online Access: | http://wjst.wu.ac.th/index.php/wjst/article/view/246 |
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| author | Muhammad Nadeem ARSHAD Muhammad ZIA-UR-REHMAN Islam Ullah KHAN Ghulam MUSTAFA Muhammad SHAFIQ Hafiz Muhammad RAFIQUE Kevin Travis HOLMAN |
| author_facet | Muhammad Nadeem ARSHAD Muhammad ZIA-UR-REHMAN Islam Ullah KHAN Ghulam MUSTAFA Muhammad SHAFIQ Hafiz Muhammad RAFIQUE Kevin Travis HOLMAN |
| author_sort | Muhammad Nadeem ARSHAD |
| collection | DOAJ |
| description | Crystal structures of methyl 2-pentyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide 1 and methyl 2-pentenyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide 2 have been determined after their synthesis from saccharin. 1 and 2 crystallize in a monoclinic and orthorhombic crystal system, respectively. The asymmetric unit of both contains one molecule of each compound and shows intramolecular O-H×××O interactions generating six membered ring motifs S11(6). Intermolecular hydrogen bonding interactions have been observed in the molecule with the pentyl side chain. The thiazine ring in both molecules adopts a half chair conformation with a r.m.s. deviation of 0.2049 Å and 0.2161 Å. |
| first_indexed | 2024-12-13T00:45:54Z |
| format | Article |
| id | doaj.art-d8917a3114a1407faace16408b51e5fd |
| institution | Directory Open Access Journal |
| issn | 1686-3933 2228-835X |
| language | English |
| last_indexed | 2024-12-13T00:45:54Z |
| publishDate | 2012-03-01 |
| publisher | Walailak University |
| record_format | Article |
| series | Walailak Journal of Science and Technology |
| spelling | doaj.art-d8917a3114a1407faace16408b51e5fd2022-12-22T00:05:02ZengWalailak UniversityWalailak Journal of Science and Technology1686-39332228-835X2012-03-019410.2004/wjst.v9i4.246223Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-DioxideMuhammad Nadeem ARSHAD0Muhammad ZIA-UR-REHMAN1Islam Ullah KHAN2Ghulam MUSTAFA3Muhammad SHAFIQ4Hafiz Muhammad RAFIQUE5Kevin Travis HOLMAN6Chemistry Department & Center of Excellence for Advanced Materials Research, Faculty of Science, King Abdulaziz University, Jeddah 215892Applied Chemistry Research Center, PCSIR Laboratories Complex, Ferozpur Road Lahore 54600Materials Chemistry Laboratory, Department of Chemistry, Government College University, Lahore 54000Department of Chemistry, University of Gujrat, Gujrat 50781Department of Chemistry, Government College University, Faisalabad 38040X-ray Diffraction and Crystallography Laboratory, Department of Physics, School of Physical Sciences, University of the Punjab, Quaid-e-Azam Campus, Lahore 54590Department of Chemistry, 240 Reiss Science Building, Georgetown University, 37th and Oth Streets NW, Washington, DC 20057-1227Crystal structures of methyl 2-pentyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide 1 and methyl 2-pentenyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide 2 have been determined after their synthesis from saccharin. 1 and 2 crystallize in a monoclinic and orthorhombic crystal system, respectively. The asymmetric unit of both contains one molecule of each compound and shows intramolecular O-H×××O interactions generating six membered ring motifs S11(6). Intermolecular hydrogen bonding interactions have been observed in the molecule with the pentyl side chain. The thiazine ring in both molecules adopts a half chair conformation with a r.m.s. deviation of 0.2049 Å and 0.2161 Å.http://wjst.wu.ac.th/index.php/wjst/article/view/24612-benzothiazinesingle crystalstructure studiesX-raysoxicam |
| spellingShingle | Muhammad Nadeem ARSHAD Muhammad ZIA-UR-REHMAN Islam Ullah KHAN Ghulam MUSTAFA Muhammad SHAFIQ Hafiz Muhammad RAFIQUE Kevin Travis HOLMAN Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide Walailak Journal of Science and Technology 1 2-benzothiazine single crystal structure studies X-rays oxicam |
| title | Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide |
| title_full | Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide |
| title_fullStr | Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide |
| title_full_unstemmed | Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide |
| title_short | Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide |
| title_sort | structural studies of 2 pentyl pentenyl substituted methyl 4 hydroxy 2h 1 2 benzothiazine 3 carboxylate 1 1 dioxide |
| topic | 1 2-benzothiazine single crystal structure studies X-rays oxicam |
| url | http://wjst.wu.ac.th/index.php/wjst/article/view/246 |
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