Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fraction
Summary: Heart failure with preserved ejection fraction is an increasing challenge for modern day medicine and has been drawing more attention recently. Invasive right heart catheterization represents the mainstay for the diagnosis of diastolic dysfunction, however due to its attributable risk of an...
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Format: | Article |
Language: | English |
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Elsevier
2022-12-01
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Series: | EBioMedicine |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396422005515 |
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author | Alexander Schulz Andreas Schuster |
author_facet | Alexander Schulz Andreas Schuster |
author_sort | Alexander Schulz |
collection | DOAJ |
description | Summary: Heart failure with preserved ejection fraction is an increasing challenge for modern day medicine and has been drawing more attention recently. Invasive right heart catheterization represents the mainstay for the diagnosis of diastolic dysfunction, however due to its attributable risk of an invasive procedure, other non-invasive clinical pathways are trying to approach this pathology in clinical practice. Diastolic failure is complex, and imaging is based on various parameters. In addition to transthoracic echocardiography, numerous novel imaging approaches, such as cardiac magnetic resonance imaging, computed tomography, positron emission (computed) tomography or single photon emission tomography techniques are being used to supplement deeper insights into causal pathology and might open targets for dedicated therapy options. This article provides insights into these sophisticated imaging techniques, their incremental value for the diagnosis of this poorly understood disease and recent promising results for an enhanced prognostication of outcome and therapy monitoring. |
first_indexed | 2024-04-13T11:56:23Z |
format | Article |
id | doaj.art-d89a15b295f74c5c8d279c65b86f03d6 |
institution | Directory Open Access Journal |
issn | 2352-3964 |
language | English |
last_indexed | 2024-04-13T11:56:23Z |
publishDate | 2022-12-01 |
publisher | Elsevier |
record_format | Article |
series | EBioMedicine |
spelling | doaj.art-d89a15b295f74c5c8d279c65b86f03d62022-12-22T02:47:55ZengElsevierEBioMedicine2352-39642022-12-0186104369Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fractionAlexander Schulz0Andreas Schuster1Department of Cardiology and Pneumology, Georg-August University, University Medical Center Göttingen, Göttingen, GermanyCorresponding author. Department for Cardiology and Pneumology, University Medical Center, Georg-August University, Robert-Koch-Str. 40, 37099 Göttingen, Germany.; Department of Cardiology and Pneumology, Georg-August University, University Medical Center Göttingen, Göttingen, GermanySummary: Heart failure with preserved ejection fraction is an increasing challenge for modern day medicine and has been drawing more attention recently. Invasive right heart catheterization represents the mainstay for the diagnosis of diastolic dysfunction, however due to its attributable risk of an invasive procedure, other non-invasive clinical pathways are trying to approach this pathology in clinical practice. Diastolic failure is complex, and imaging is based on various parameters. In addition to transthoracic echocardiography, numerous novel imaging approaches, such as cardiac magnetic resonance imaging, computed tomography, positron emission (computed) tomography or single photon emission tomography techniques are being used to supplement deeper insights into causal pathology and might open targets for dedicated therapy options. This article provides insights into these sophisticated imaging techniques, their incremental value for the diagnosis of this poorly understood disease and recent promising results for an enhanced prognostication of outcome and therapy monitoring.http://www.sciencedirect.com/science/article/pii/S2352396422005515HFpEFDiastolic dysfunctionNon-invasive imagingImaging markers |
spellingShingle | Alexander Schulz Andreas Schuster Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fraction EBioMedicine HFpEF Diastolic dysfunction Non-invasive imaging Imaging markers |
title | Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fraction |
title_full | Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fraction |
title_fullStr | Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fraction |
title_full_unstemmed | Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fraction |
title_short | Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fraction |
title_sort | visualizing diastolic failure non invasive imaging biomarkers in patients with heart failure with preserved ejection fraction |
topic | HFpEF Diastolic dysfunction Non-invasive imaging Imaging markers |
url | http://www.sciencedirect.com/science/article/pii/S2352396422005515 |
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