From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant Recipient
Human adenovirus infection is rare in adult population, except for in immunocompromised individuals. Recipients of allogenic haploidentical hematopoietic stem cell transplantation are reported at high risk for human adenovirus, which is often lethal when it evolves into the disseminated form. Despit...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Pathogens |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/10/3/340 |
| _version_ | 1797541362483068928 |
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| author | Baptiste Demey Clément Brault Julien Maizel Catherine Francois |
| author_facet | Baptiste Demey Clément Brault Julien Maizel Catherine Francois |
| author_sort | Baptiste Demey |
| collection | DOAJ |
| description | Human adenovirus infection is rare in adult population, except for in immunocompromised individuals. Recipients of allogenic haploidentical hematopoietic stem cell transplantation are reported at high risk for human adenovirus, which is often lethal when it evolves into the disseminated form. Despite existent guidelines, prevention, early diagnosis, and therapeutics remain challenging. Here, we report the case of a fatal evolution of human adenovirus respiratory infection and discuss the actual recommendations to prevent recurrence of this major issue. |
| first_indexed | 2024-03-10T13:14:54Z |
| format | Article |
| id | doaj.art-d89c08217fd24681aae27a736c78dbf4 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T13:14:54Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-d89c08217fd24681aae27a736c78dbf42023-11-21T10:31:21ZengMDPI AGPathogens2076-08172021-03-0110334010.3390/pathogens10030340From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant RecipientBaptiste Demey0Clément Brault1Julien Maizel2Catherine Francois3Department of Virology, Amiens University Medical Center, 80000 Amiens, FranceIntensive Care Department, Amiens University Medical Center, 80000 Amiens, FranceIntensive Care Department, Amiens University Medical Center, 80000 Amiens, FranceDepartment of Virology, Amiens University Medical Center, 80000 Amiens, FranceHuman adenovirus infection is rare in adult population, except for in immunocompromised individuals. Recipients of allogenic haploidentical hematopoietic stem cell transplantation are reported at high risk for human adenovirus, which is often lethal when it evolves into the disseminated form. Despite existent guidelines, prevention, early diagnosis, and therapeutics remain challenging. Here, we report the case of a fatal evolution of human adenovirus respiratory infection and discuss the actual recommendations to prevent recurrence of this major issue.https://www.mdpi.com/2076-0817/10/3/340adenovirushematopoietic stem cell transplantlymphohistiocytosisrespiratory infection |
| spellingShingle | Baptiste Demey Clément Brault Julien Maizel Catherine Francois From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant Recipient Pathogens adenovirus hematopoietic stem cell transplant lymphohistiocytosis respiratory infection |
| title | From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant Recipient |
| title_full | From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant Recipient |
| title_fullStr | From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant Recipient |
| title_full_unstemmed | From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant Recipient |
| title_short | From Upper Respiratory Symptoms to Hemophagocytic Lymphohistiocytosis: Case Report of a Human Adenovirus Infection in Haploidentical Hematopoietic Stem Cell Transplant Recipient |
| title_sort | from upper respiratory symptoms to hemophagocytic lymphohistiocytosis case report of a human adenovirus infection in haploidentical hematopoietic stem cell transplant recipient |
| topic | adenovirus hematopoietic stem cell transplant lymphohistiocytosis respiratory infection |
| url | https://www.mdpi.com/2076-0817/10/3/340 |
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