INHIBITION OF IN VITRO NITROSATION OF NORNICOTINE
The inhibition of nornicotine nitrosation was studied. The concentration of nornicotine was 100 μM and nitrite 1000 μM. As inhibitors were used following compounds: ascorbic acid (as reference) (800, 1000, and 5000 μM), dihydroxyfumaric acid (1000 μM), (+)catechin (1000 μM), resveratrol (1000 μM), t...
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| Format: | Article |
| Language: | English |
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Academy of Sciences of Moldova, Institute of Chemistry
2007-06-01
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| Series: | Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry |
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| Online Access: | http://www.cjm.asm.md/sites/default/files/article_files/11_Porubin_0.pdf |
| _version_ | 1818979112671248384 |
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| author | Diana Porubin |
| author_facet | Diana Porubin |
| author_sort | Diana Porubin |
| collection | DOAJ |
| description | The inhibition of nornicotine nitrosation was studied. The concentration of nornicotine was 100 μM and nitrite 1000 μM. As inhibitors were used following compounds: ascorbic acid (as reference) (800, 1000, and 5000 μM), dihydroxyfumaric acid (1000 μM), (+)catechin (1000 μM), resveratrol (1000 μM), tartaric acid (1000 μM), quercetin (1000 μM), and grape seed extract (50, 100, 150 μg/ml). The best inhibitory effect was obtained for AAs at 5000 μM (90.7%), (+)Ct (95.5 %) and GSE at 150 μg/ml (96.1%). The small inhibitory effect was observed for TA – 22,5%. |
| first_indexed | 2024-12-20T16:54:21Z |
| format | Article |
| id | doaj.art-d89c58de357a4dfea333c4d9805d32f8 |
| institution | Directory Open Access Journal |
| issn | 1857-1727 2345-1688 |
| language | English |
| last_indexed | 2024-12-20T16:54:21Z |
| publishDate | 2007-06-01 |
| publisher | Academy of Sciences of Moldova, Institute of Chemistry |
| record_format | Article |
| series | Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry |
| spelling | doaj.art-d89c58de357a4dfea333c4d9805d32f82022-12-21T19:32:46ZengAcademy of Sciences of Moldova, Institute of ChemistryChemistry Journal of Moldova: General, Industrial and Ecological Chemistry1857-17272345-16882007-06-01217882INHIBITION OF IN VITRO NITROSATION OF NORNICOTINEDiana Porubin0State University of MoldovaThe inhibition of nornicotine nitrosation was studied. The concentration of nornicotine was 100 μM and nitrite 1000 μM. As inhibitors were used following compounds: ascorbic acid (as reference) (800, 1000, and 5000 μM), dihydroxyfumaric acid (1000 μM), (+)catechin (1000 μM), resveratrol (1000 μM), tartaric acid (1000 μM), quercetin (1000 μM), and grape seed extract (50, 100, 150 μg/ml). The best inhibitory effect was obtained for AAs at 5000 μM (90.7%), (+)Ct (95.5 %) and GSE at 150 μg/ml (96.1%). The small inhibitory effect was observed for TA – 22,5%.http://www.cjm.asm.md/sites/default/files/article_files/11_Porubin_0.pdfN-nitrosonornicotinenitrosationinhibitiongrape seed extractpolyphenol |
| spellingShingle | Diana Porubin INHIBITION OF IN VITRO NITROSATION OF NORNICOTINE Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry N-nitrosonornicotine nitrosation inhibition grape seed extract polyphenol |
| title | INHIBITION OF IN VITRO NITROSATION OF NORNICOTINE |
| title_full | INHIBITION OF IN VITRO NITROSATION OF NORNICOTINE |
| title_fullStr | INHIBITION OF IN VITRO NITROSATION OF NORNICOTINE |
| title_full_unstemmed | INHIBITION OF IN VITRO NITROSATION OF NORNICOTINE |
| title_short | INHIBITION OF IN VITRO NITROSATION OF NORNICOTINE |
| title_sort | inhibition of in vitro nitrosation of nornicotine |
| topic | N-nitrosonornicotine nitrosation inhibition grape seed extract polyphenol |
| url | http://www.cjm.asm.md/sites/default/files/article_files/11_Porubin_0.pdf |
| work_keys_str_mv | AT dianaporubin inhibitionofinvitronitrosationofnornicotine |