Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients

Chronic infection perturbs immune homeostasis. While prior studies have reported dysregulation of effector and memory cells, little is known about the effects on naïve T cell populations. We performed a cross-sectional study of chronic hepatitis C (cHCV) patients using tetramer-associated magnetic e...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Cécile Alanio, Francesco Nicoli, Philippe Sultanik, Tobias Flecken, Brieuc Perot, Darragh Duffy, Elisabetta Bianchi, Annick Lim, Emmanuel Clave, Marit M van Buuren, Aurélie Schnuriger, Kerstin Johnsson, Jeremy Boussier, Antoine Garbarg-Chenon, Laurence Bousquet, Estelle Mottez, Ton N Schumacher, Antoine Toubert, Victor Appay, Farhad Heshmati, Robert Thimme, Stanislas Pol, Vincent Mallet, Matthew L Albert
Formáid:	Alt
Teanga:	English
Foilsithe / Cruthaithe:	eLife Sciences Publications Ltd 2015-11-01
Sraith:	eLife
Ábhair:	Pre-immune repertoire CD8 T cell dysfunction TCR signaling viral immunology chronic inflammation
Rochtain ar líne:	https://elifesciences.org/articles/07916

Míreanna comhchosúla

Rotavirus rearranged genomic RNA segments are preferentially packaged into viruses despite not conferring selective growth advantage to viruses.
de réir: Cécile Troupin, et al.
Foilsithe / Cruthaithe: (2011-01-01)

Naïve CD8+ T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8+ T-Cells
de réir: Francesco Nicoli, et al.
Foilsithe / Cruthaithe: (2018-12-01)

Postresuscitative Myocardial Impact of Anatoxin Preimmunization
de réir: D. A. Yenikeyev, et al.
Foilsithe / Cruthaithe: (2007-12-01)

Expansion of the preimmune antibody repertoire by junctional diversity in Bos taurus.
de réir: Jenni Liljavirta, et al.
Foilsithe / Cruthaithe: (2014-01-01)

Experience with Use of Immunomodulators in Treatment of Tonsillitis Developed at the Background of Preimmunization by Teovac
de réir: V. P. Bondarev, et al.
Foilsithe / Cruthaithe: (2020-05-01)

Preimmunization correlates of protection shared across malaria vaccine trials in adults
de réir: Maxwell L. Neal, et al.
Foilsithe / Cruthaithe: (2022-01-01)

Potential SARS-CoV-2 Preimmune IgM Epitopes
de réir: Velizar Shivarov, et al.
Foilsithe / Cruthaithe: (2020-04-01)

Demographic and clinical factors associated with response to smallpox vaccine in preimmunized volunteers.
de réir: Philippe Bossi, et al.
Foilsithe / Cruthaithe: (2008-01-01)

PROLIFERATION RESPONSES IN PREIMMUNIZED MICE LYMPHOCYTES BY BORDETELLA PERTUSSIS CELL WALL COMPONENTS
de réir: Ashraf Mohabbati Mobarez, et al.
Foilsithe / Cruthaithe: (2003-03-01)

Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old
de réir: Francesco Nicoli, et al.
Foilsithe / Cruthaithe: (2022-02-01)

Human herpesvirus-8 infection leads to expansion of the preimmune/natural effector B cell compartment.
de réir: Silvia Della Bella, et al.
Foilsithe / Cruthaithe: (2010-11-01)

Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post‐translational modification: prospective placebo‐controlled clinical studies
de réir: Jérémie Decalf, et al.
Foilsithe / Cruthaithe: (2016-04-01)

Back to the Future for Influenza Preimmunity—Looking Back at Influenza Virus History to Infer the Outcome of Future Infections
de réir: Magen Ellen Francis, et al.
Foilsithe / Cruthaithe: (2019-01-01)

Evaluation of the protective capacity of new mild Citrus tristeza virus (CTV) isolates selected for a preimmunization program
de réir: Carlos Alexandre Zanutto, et al.
Foilsithe / Cruthaithe: (2013-04-01)

A dormant cancer mouse model established by combining preimmune strategy with mVenus-p27K- system
de réir: Musitaba MUTAILIFU, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Grand challenges in alloimmunity and transplantation
de réir: Antoine eToubert
Foilsithe / Cruthaithe: (2011-08-01)

Preimmunization with Listeria-vectored cervical cancer vaccine candidate strains can establish specific T-cell immune memory and prevent tumorigenesis
de réir: Yunwen Zhang, et al.
Foilsithe / Cruthaithe: (2024-03-01)

Broadly Reactive H2 Hemagglutinin Vaccines Elicit Cross-Reactive Antibodies in Ferrets Preimmune to Seasonal Influenza A Viruses
de réir: Z. Beau Reneer, et al.
Foilsithe / Cruthaithe: (2021-04-01)

Enhancement of rat spermatozoal hyperactivation by progesterone
de réir: Yuki MIYAZAWA, et al.
Foilsithe / Cruthaithe: (2023-09-01)

Flagellar hyperactivation of bull and boar spermatozoa
de réir: Hiroshi Harayama
Foilsithe / Cruthaithe: (2018-10-01)

Editorial: Tailoring NK Cell Receptor–Ligand Interactions: An Art in Evolution
de réir: Ulrike Koehl, et al.
Foilsithe / Cruthaithe: (2018-02-01)

Serotonergic signals enhanced hamster sperm hyperactivation
de réir: Chiyori SAKAMOTO, et al.
Foilsithe / Cruthaithe: (2021-05-01)

Harnessing the Induction of CD8+ T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in Antigen Presenting Cells
de réir: Francesco Nicoli, et al.
Foilsithe / Cruthaithe: (2018-10-01)

Hyperactivation of crosslinked lipases in elastic hydroxyapatite microgel and their properties
de réir: Hyo Won Jeon, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Protein kinases regulate hyperactivated motility of human sperm
de réir: Ya-Yan Wang, et al.
Foilsithe / Cruthaithe: (2021-10-01)

Eugenol-hyperactivated nymphs of Triatoma infestans become intoxicated faster than non-hyperactivated nymphs when exposed to a permethrin-treated surface
de réir: Mercedes María Noel Reynoso, et al.
Foilsithe / Cruthaithe: (2018-11-01)

Editorial: Immune Profile After Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Diseases: Where Do We Stand?
de réir: Kelen Cristina Ribeiro Malmegrim, et al.
Foilsithe / Cruthaithe: (2020-01-01)

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells
de réir: Zhang, Bing, et al.
Foilsithe / Cruthaithe: (2020)

Modelling a tethered mammalian sperm cell undergoing hyperactivation.
de réir: Curtis, M, et al.
Foilsithe / Cruthaithe: (2012)

Neural hyperactivation in carriers of the Alzheimer's risk variant on the clusterin gene.
de réir: Lancaster, T, et al.
Foilsithe / Cruthaithe: (2011)

Brain morphological analysis in mice with hyperactivation of the hedgehog signaling pathway
de réir: Tadashi Shiohama, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Molecular mechanism of hyperactivation conferred by a truncation of TRPA1
de réir: Avnika Bali, et al.
Foilsithe / Cruthaithe: (2023-05-01)

Effects of 5-hydroxytryptamine on spermatozoal hyperactivation and in vitro fertilization in mice
de réir: Yukiko SUGIYAMA, et al.
Foilsithe / Cruthaithe: (2019-11-01)

Hyperactivation in the habenula as a link between depression and sleep disturbance
de réir: Hidenori eAizawa, et al.
Foilsithe / Cruthaithe: (2013-12-01)

Greatwall promotes cell transformation by hyperactivating AKT in human malignancies
de réir: Jorge Vera, et al.
Foilsithe / Cruthaithe: (2015-11-01)

Behavioral mechanism during human sperm chemotaxis: involvement of hyperactivation.
de réir: Leah Armon, et al.
Foilsithe / Cruthaithe: (2011-01-01)

Dysfunctional GABAergic inhibition in the prefrontal cortex leading to "psychotic" hyperactivation
de réir: Tanaka Shoji
Foilsithe / Cruthaithe: (2008-04-01)

The pressure tensor in tangential equilibria
de réir: F. Mottez
Foilsithe / Cruthaithe: (2004-09-01)

Non-propagating electric and density structures formed through non-linear interaction of Alfvén waves
de réir: F. Mottez
Foilsithe / Cruthaithe: (2012-01-01)

NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment
de réir: Alexandra Frazao, et al.
Foilsithe / Cruthaithe: (2019-03-01)