Proliferating CD8<sup>+</sup> T Cell Infiltrates Are Associated with Improved Survival in Glioblastoma

Proliferating CD8<sup>+</sup> T Cell Infiltrates Are Associated with Improved Survival in Glioblastoma

Background: tumor-infiltrating lymphocytes are prognostic in many human cancers. However, the prognostic value of lymphocytes infiltrating glioblastoma (GBM), and roles in tumor control or progression are unclear. We hypothesized that B and T cell density, and markers of their activity, proliferatio...

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Bibliographic Details
Main Authors: Ileana S. Mauldin, Jasmin Jo, Nolan A. Wages, Lalanthica V. Yogendran, Adela Mahmutovic, Samuel J. Young, Maria Beatriz Lopes, Craig L. Slingluff, Loren D. Erickson, Camilo E. Fadul
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
immunology
tumor infiltrating lymphocytes
multiplex immunofluorescence histology
glioblastoma
human
Online Access:https://www.mdpi.com/2073-4409/10/12/3378

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