A Meta-Analysis of The Prevalence and Etiology of Infertility in Iran
Infertility is a serious health issue in the world affecting approximately 8-10% of couples worldwide. The meta-analysisstudy was performed to assess the prevalence and etiologic factors associated with infertility in Iran. We made surethat the implementation of study and reporting the results were...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Royan Institute (ACECR), Tehran
2023-04-01
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| Series: | International Journal of Fertility and Sterility |
| Subjects: | |
| Online Access: | https://www.ijfs.ir/article_701184_b61354228104c57798cdf923b528bd2a.pdf |
| _version_ | 1797826729049325568 |
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| author | Ghobad Abangah Tayebeh Rashidian Marziyeh Parizad Nasirkandy Milad Azami |
| author_facet | Ghobad Abangah Tayebeh Rashidian Marziyeh Parizad Nasirkandy Milad Azami |
| author_sort | Ghobad Abangah |
| collection | DOAJ |
| description | Infertility is a serious health issue in the world affecting approximately 8-10% of couples worldwide. The meta-analysisstudy was performed to assess the prevalence and etiologic factors associated with infertility in Iran. We made surethat the implementation of study and reporting the results were consistent with the MOOSE and PRISMA guidelines,respectively. All stages of the research were conducted by two authors, and the disagreement at each stage of the researchwas resolved by consensus. On January 1, 2020, we started a detailed literature search on international onlinedatabases, and Iranian Online databases, as well as specialized journals, several authentic international publishers andGoogle Scholar. We reviewed the reference list of identified articles for missed articles and then searched online forthem. Data analysis was performed to estimate the prevalence using a random effects model. The lifetime infertilityprevalence was found to be 11.3% [95% confidence interval (CI): 8.6-14.7] and the current infertility was evaluated tobe 3.7% (95% CI: 3.2-4.3). The prevalence of primary infertility (based on 45 articles consisting of 51,021 samples)as well as secondary infertility (based on 13 articles consisting of 35,683 samples) in Iran were estimated to be 18.3%(95% CI: 15.4-21.6) and 2.5% (95% CI: 1.6-4.0), respectively. The prevalence of female, male, both and unexplainedcauses was estimated to be 32.0% (95% CI: 27.6-36.8), 43.3% (95% CI: 38.2-48.6), 12.5% (95% CI: 9.6-16.2) and13.6% (95% CI: 10.2-17.8), respectively. The prevalence of causes related to ovulation, uterine tubes, and endometriosisin infertile women was estimated to be 54.0% (95% CI: 45.6-62.2), 15.5% (95% CI: 11.3-21.0), 6.2% (95%CI: 3.5-10.6), and 5.4% (95% CI: 2.5-11.3), respectively. In summary, the estimate of infertility burden in Iran didnot change between 1990 and 2017 and its prevalence remains high. This research presents a unified and up-to-dateoverview regarding the burden of infertility in Iran. |
| first_indexed | 2024-04-09T12:36:56Z |
| format | Article |
| id | doaj.art-d8a15479ab054ad1bd27b4a073a6cc97 |
| institution | Directory Open Access Journal |
| issn | 2008-076X 2008-0778 |
| language | English |
| last_indexed | 2024-04-09T12:36:56Z |
| publishDate | 2023-04-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | International Journal of Fertility and Sterility |
| spelling | doaj.art-d8a15479ab054ad1bd27b4a073a6cc972023-05-15T10:41:33ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782023-04-0117316017310.22074/ijfs.2023.541991.1215701184A Meta-Analysis of The Prevalence and Etiology of Infertility in IranGhobad Abangah0Tayebeh Rashidian1Marziyeh Parizad Nasirkandy2Milad Azami3Department of Gastroenterology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, IranDepartment of Obstetrics and Gynecology, School of Medicine, Ilam University of Medical Sciences, Ilam, IranDepartment of Obstetrics and Gynecology, Women’s Reproductive Health Research Center, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Gastroenterology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, IranInfertility is a serious health issue in the world affecting approximately 8-10% of couples worldwide. The meta-analysisstudy was performed to assess the prevalence and etiologic factors associated with infertility in Iran. We made surethat the implementation of study and reporting the results were consistent with the MOOSE and PRISMA guidelines,respectively. All stages of the research were conducted by two authors, and the disagreement at each stage of the researchwas resolved by consensus. On January 1, 2020, we started a detailed literature search on international onlinedatabases, and Iranian Online databases, as well as specialized journals, several authentic international publishers andGoogle Scholar. We reviewed the reference list of identified articles for missed articles and then searched online forthem. Data analysis was performed to estimate the prevalence using a random effects model. The lifetime infertilityprevalence was found to be 11.3% [95% confidence interval (CI): 8.6-14.7] and the current infertility was evaluated tobe 3.7% (95% CI: 3.2-4.3). The prevalence of primary infertility (based on 45 articles consisting of 51,021 samples)as well as secondary infertility (based on 13 articles consisting of 35,683 samples) in Iran were estimated to be 18.3%(95% CI: 15.4-21.6) and 2.5% (95% CI: 1.6-4.0), respectively. The prevalence of female, male, both and unexplainedcauses was estimated to be 32.0% (95% CI: 27.6-36.8), 43.3% (95% CI: 38.2-48.6), 12.5% (95% CI: 9.6-16.2) and13.6% (95% CI: 10.2-17.8), respectively. The prevalence of causes related to ovulation, uterine tubes, and endometriosisin infertile women was estimated to be 54.0% (95% CI: 45.6-62.2), 15.5% (95% CI: 11.3-21.0), 6.2% (95%CI: 3.5-10.6), and 5.4% (95% CI: 2.5-11.3), respectively. In summary, the estimate of infertility burden in Iran didnot change between 1990 and 2017 and its prevalence remains high. This research presents a unified and up-to-dateoverview regarding the burden of infertility in Iran.https://www.ijfs.ir/article_701184_b61354228104c57798cdf923b528bd2a.pdfetiologyinfertilityiranprevalence |
| spellingShingle | Ghobad Abangah Tayebeh Rashidian Marziyeh Parizad Nasirkandy Milad Azami A Meta-Analysis of The Prevalence and Etiology of Infertility in Iran International Journal of Fertility and Sterility etiology infertility iran prevalence |
| title | A Meta-Analysis of The Prevalence and Etiology of Infertility in Iran |
| title_full | A Meta-Analysis of The Prevalence and Etiology of Infertility in Iran |
| title_fullStr | A Meta-Analysis of The Prevalence and Etiology of Infertility in Iran |
| title_full_unstemmed | A Meta-Analysis of The Prevalence and Etiology of Infertility in Iran |
| title_short | A Meta-Analysis of The Prevalence and Etiology of Infertility in Iran |
| title_sort | meta analysis of the prevalence and etiology of infertility in iran |
| topic | etiology infertility iran prevalence |
| url | https://www.ijfs.ir/article_701184_b61354228104c57798cdf923b528bd2a.pdf |
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