ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells

ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells

Abstract The proliferation of vascular smooth muscle cells (VSMCs) is one of the key events during the progress of atherosclerosis. The activated liver X receptor (LXR) signalling pathway is demonstrated to inhibit platelet-derived growth factor BB (PDGF-BB)-induced VSMC proliferation. Notably, foll...

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Bibliographic Details
Main Authors: Xu Huang, Meng-Qi Xu, Wei Zhang, Sai Ma, Weisheng Guo, Yabin Wang, Yan Zhang, Tiantian Gou, Yundai Chen, Xing-Jie Liang, Feng Cao
Format: Article
Language:English
Published: SpringerOpen 2017-05-01
Series:Nanoscale Research Letters
Subjects:
Vascular smooth muscle cells
Liver X receptor
ICAM-1
Liposome
Online Access:http://link.springer.com/article/10.1186/s11671-017-2097-6

Internet

http://link.springer.com/article/10.1186/s11671-017-2097-6

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