Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to Treatment

DNA fingerprinting has demonstrated predominance of the Beijing genotype among Mycobacterium tuberculosis strains isolated in Southeast Asia. We prospectively examined the occurrence of Beijing genotype strains in tuberculosis patients in Indonesia. Early in treatment, patients infected with Beijing...

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Main Authors: Reinout van Crevel, Ron H.H. Nelwan, Wilma de Lenne, Yelilsan Veeraragu, Adri G. van der Zanden, Zulkifli Amin, Jos W.M. van der Meer, Dick van Soolingen
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2001-10-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/7/5/01-7518_article
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author Reinout van Crevel
Ron H.H. Nelwan
Wilma de Lenne
Yelilsan Veeraragu
Adri G. van der Zanden
Zulkifli Amin
Jos W.M. van der Meer
Dick van Soolingen
author_facet Reinout van Crevel
Ron H.H. Nelwan
Wilma de Lenne
Yelilsan Veeraragu
Adri G. van der Zanden
Zulkifli Amin
Jos W.M. van der Meer
Dick van Soolingen
author_sort Reinout van Crevel
collection DOAJ
description DNA fingerprinting has demonstrated predominance of the Beijing genotype among Mycobacterium tuberculosis strains isolated in Southeast Asia. We prospectively examined the occurrence of Beijing genotype strains in tuberculosis patients in Indonesia. Early in treatment, patients infected with Beijing genotype strains more often had fever unrelated to disease severity, toxicity, or drug resistance, indicating that Beijing genotype strains may have specific pathogenic properties.
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spelling doaj.art-d8a818e526ae4a3f88e4cabf4a89bfaa2022-12-22T02:00:47ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592001-10-017588088310.3201/eid0705.017518Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to TreatmentReinout van CrevelRon H.H. NelwanWilma de LenneYelilsan VeeraraguAdri G. van der ZandenZulkifli AminJos W.M. van der MeerDick van SoolingenDNA fingerprinting has demonstrated predominance of the Beijing genotype among Mycobacterium tuberculosis strains isolated in Southeast Asia. We prospectively examined the occurrence of Beijing genotype strains in tuberculosis patients in Indonesia. Early in treatment, patients infected with Beijing genotype strains more often had fever unrelated to disease severity, toxicity, or drug resistance, indicating that Beijing genotype strains may have specific pathogenic properties.https://wwwnc.cdc.gov/eid/article/7/5/01-7518_articletuberculosisMycobacterium tuberculosisDNA fingerprintingdrug resistancevirulenceimmune response
spellingShingle Reinout van Crevel
Ron H.H. Nelwan
Wilma de Lenne
Yelilsan Veeraragu
Adri G. van der Zanden
Zulkifli Amin
Jos W.M. van der Meer
Dick van Soolingen
Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to Treatment
Emerging Infectious Diseases
tuberculosis
Mycobacterium tuberculosis
DNA fingerprinting
drug resistance
virulence
immune response
title Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to Treatment
title_full Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to Treatment
title_fullStr Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to Treatment
title_full_unstemmed Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to Treatment
title_short Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to Treatment
title_sort mycobacterium tuberculosis beijing genotype strains associated with febrile response to treatment
topic tuberculosis
Mycobacterium tuberculosis
DNA fingerprinting
drug resistance
virulence
immune response
url https://wwwnc.cdc.gov/eid/article/7/5/01-7518_article
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