From Illness to Resilience: Mediating Factors of Quality of Life in Patients with Congenital Heart Disease
Background: Congenital heart disease (CHD) is a leading cause of childhood morbidity, with an estimated prevalence of 0.8–1%. However, advances in diagnosis and treatment now allow 90% of childhood CHD patients to survive to adulthood, leading to increased interest in their quality of life (QoL). In...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2023-08-01
|
| Series: | Reviews in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/RCM/24/8/10.31083/j.rcm2408224 |
| _version_ | 1797733161329754112 |
|---|---|
| author | Fernanda Moedas Filipa Nunes Paula Brito Ana Bessa Sara Espírito Santo Sara Soares Marisa Pereira Victor Viana Bruno Peixoto Joana O Miranda José Carlos Areias Maria Emília G. Areias |
| author_facet | Fernanda Moedas Filipa Nunes Paula Brito Ana Bessa Sara Espírito Santo Sara Soares Marisa Pereira Victor Viana Bruno Peixoto Joana O Miranda José Carlos Areias Maria Emília G. Areias |
| author_sort | Fernanda Moedas |
| collection | DOAJ |
| description | Background: Congenital heart disease (CHD) is a leading cause of childhood morbidity, with an estimated prevalence of 0.8–1%. However, advances in diagnosis and treatment now allow 90% of childhood CHD patients to survive to adulthood, leading to increased interest in their quality of life (QoL). In this study, we examine the impact of clinical and psychosocial variables, including the number of surgical interventions (NSI), age at surgery, school achievement, and social support, as mediating factors of QoL in CHD patients. Methods: The study included 233 CHD patients (132 males) with an average age of 15.2 ± 2.07 years, including 80 with cyanotic CHD and 153 with acyanotic CHD. The severity of illness ranged from mild to severe, with 30 patients having a severe illness, 119 having a moderate illness, and 84 having a mild illness. One-hundred-sixty-three patients underwent surgery. Clinical data on diagnosis, the severity of CHD, the type of CHD, and surgical interventions were collected from patient records, and a semi-structured interview was conducted to explore the relationship between CHD diagnosis and various aspects of life. QoL was assessed using the Abbreviated World Health Organization Quality of Life questionnaire (WHOQOL-Bref) questionnaire. Results: Ten mediation models were analyzed, each with three hypotheses (paths). In all models the first hypothesis was supported. Analyses of the second and third hypotheses revealed three feasible models of mediation through the effect of NSI on QoL in CHD patients. Conclusions: Our findings indicate that patients with more severe and cyanotic CHD generally require more surgical interventions, which may increase the risk of negative outcomes and affect patients’ perception of QoL. These results have important implications for healthcare providers and psychologists who work with childhood CHD patients. |
| first_indexed | 2024-03-12T12:25:09Z |
| format | Article |
| id | doaj.art-d8a91a1baa0b4c4bb70f1fba835de9a7 |
| institution | Directory Open Access Journal |
| issn | 1530-6550 |
| language | English |
| last_indexed | 2024-03-12T12:25:09Z |
| publishDate | 2023-08-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj.art-d8a91a1baa0b4c4bb70f1fba835de9a72023-08-30T02:44:47ZengIMR PressReviews in Cardiovascular Medicine1530-65502023-08-0124822410.31083/j.rcm2408224S1530-6550(23)00998-5From Illness to Resilience: Mediating Factors of Quality of Life in Patients with Congenital Heart DiseaseFernanda Moedas0Filipa Nunes1Paula Brito2Ana Bessa3Sara Espírito Santo4Sara Soares5Marisa Pereira6Victor Viana7Bruno Peixoto8Joana O Miranda9José Carlos Areias10Maria Emília G. Areias11Department of Social and Behavioral Sciences of the University Institute of Health Sciences-CESPU, 4585-116 Gandra, PortugalDepartment of Social and Behavioral Sciences of the University Institute of Health Sciences-CESPU, 4585-116 Gandra, PortugalDepartment of Social and Behavioral Sciences of the University Institute of Health Sciences-CESPU, 4585-116 Gandra, PortugalDepartment of Social and Behavioral Sciences of the University Institute of Health Sciences-CESPU, 4585-116 Gandra, PortugalDepartment of Social and Behavioral Sciences of the University Institute of Health Sciences-CESPU, 4585-116 Gandra, PortugalDepartment of Social and Behavioral Sciences of the University Institute of Health Sciences-CESPU, 4585-116 Gandra, PortugalDepartment of Pediatric Cardiology, University Hospital Center S. João, 4200-319 Porto, PortugalDepartment of Pediatrics, University Hospital Center S. João, 4200-319 Porto, PortugalDepartment of Social and Behavioral Sciences of the University Institute of Health Sciences-CESPU, 4585-116 Gandra, PortugalDepartment of Pediatric Cardiology, University Hospital Center S. João, 4200-319 Porto, PortugalUnIC@RISE, Faculty of Medicine, University of Porto, 4050-526 Porto, PortugalUnIC@RISE, Faculty of Medicine, University of Porto, 4050-526 Porto, PortugalBackground: Congenital heart disease (CHD) is a leading cause of childhood morbidity, with an estimated prevalence of 0.8–1%. However, advances in diagnosis and treatment now allow 90% of childhood CHD patients to survive to adulthood, leading to increased interest in their quality of life (QoL). In this study, we examine the impact of clinical and psychosocial variables, including the number of surgical interventions (NSI), age at surgery, school achievement, and social support, as mediating factors of QoL in CHD patients. Methods: The study included 233 CHD patients (132 males) with an average age of 15.2 ± 2.07 years, including 80 with cyanotic CHD and 153 with acyanotic CHD. The severity of illness ranged from mild to severe, with 30 patients having a severe illness, 119 having a moderate illness, and 84 having a mild illness. One-hundred-sixty-three patients underwent surgery. Clinical data on diagnosis, the severity of CHD, the type of CHD, and surgical interventions were collected from patient records, and a semi-structured interview was conducted to explore the relationship between CHD diagnosis and various aspects of life. QoL was assessed using the Abbreviated World Health Organization Quality of Life questionnaire (WHOQOL-Bref) questionnaire. Results: Ten mediation models were analyzed, each with three hypotheses (paths). In all models the first hypothesis was supported. Analyses of the second and third hypotheses revealed three feasible models of mediation through the effect of NSI on QoL in CHD patients. Conclusions: Our findings indicate that patients with more severe and cyanotic CHD generally require more surgical interventions, which may increase the risk of negative outcomes and affect patients’ perception of QoL. These results have important implications for healthcare providers and psychologists who work with childhood CHD patients.https://www.imrpress.com/journal/RCM/24/8/10.31083/j.rcm2408224congenital heart diseaseseverityquality of lifenumber of surgical interventionsmediation models |
| spellingShingle | Fernanda Moedas Filipa Nunes Paula Brito Ana Bessa Sara Espírito Santo Sara Soares Marisa Pereira Victor Viana Bruno Peixoto Joana O Miranda José Carlos Areias Maria Emília G. Areias From Illness to Resilience: Mediating Factors of Quality of Life in Patients with Congenital Heart Disease Reviews in Cardiovascular Medicine congenital heart disease severity quality of life number of surgical interventions mediation models |
| title | From Illness to Resilience: Mediating Factors of Quality of Life in Patients with Congenital Heart Disease |
| title_full | From Illness to Resilience: Mediating Factors of Quality of Life in Patients with Congenital Heart Disease |
| title_fullStr | From Illness to Resilience: Mediating Factors of Quality of Life in Patients with Congenital Heart Disease |
| title_full_unstemmed | From Illness to Resilience: Mediating Factors of Quality of Life in Patients with Congenital Heart Disease |
| title_short | From Illness to Resilience: Mediating Factors of Quality of Life in Patients with Congenital Heart Disease |
| title_sort | from illness to resilience mediating factors of quality of life in patients with congenital heart disease |
| topic | congenital heart disease severity quality of life number of surgical interventions mediation models |
| url | https://www.imrpress.com/journal/RCM/24/8/10.31083/j.rcm2408224 |
| work_keys_str_mv | AT fernandamoedas fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT filipanunes fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT paulabrito fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT anabessa fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT saraespiritosanto fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT sarasoares fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT marisapereira fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT victorviana fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT brunopeixoto fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT joanaomiranda fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT josecarlosareias fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease AT mariaemiliagareias fromillnesstoresiliencemediatingfactorsofqualityoflifeinpatientswithcongenitalheartdisease |