Study of the relation between speckle tracking echocardiography and BODE index in patients with chronic obstructive pulmonary disease
Background Chronic obstructive pulmonary disease (COPD) is a widespread lung disease with a high mortality and morbidity especially with co-morbid cardiac impairment. Severity of COPD can be assessed using BODE Index (body mass index, obstruction of airflow, dyspnea degree and exercise capacity). Ai...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Egyptian Journal of Chest Disease and Tuberculosis |
| Subjects: | |
| Online Access: | http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2020;volume=69;issue=3;spage=524;epage=531;aulast=Fahim |
| _version_ | 1818203844143742976 |
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| author | Osama Fahim Aalaa Fawzi Morad Beshay Maha Yousif |
| author_facet | Osama Fahim Aalaa Fawzi Morad Beshay Maha Yousif |
| author_sort | Osama Fahim |
| collection | DOAJ |
| description | Background Chronic obstructive pulmonary disease (COPD) is a widespread lung disease with a high mortality and morbidity especially with co-morbid cardiac impairment. Severity of COPD can be assessed using BODE Index (body mass index, obstruction of airflow, dyspnea degree and exercise capacity).
Aim To study the relationship between BODE index and right ventricle (RV) and left ventricle (LV) functions using Two-dimensional speckle-tracking echocardiography (2D-STE) in COPD patients.
Subjects and methods Fifty stable COPD patients and matched fifty control subjects underwent transthoracic echocardiography, where conventional and speckle tracking parameters were taken. BODE indices were calculated and divided to quartiles (Q) (Q1; BODE index = 0–2, Q2; BODE index = 3–4 Q3; BODE index = 5–6, Q4; BODE index = 7–10).
Results COPD patients had lower RV fractional area change (FAC%, P<0.0001), tricuspid annular plane systolic excursion (TAPSE, P<0.0001), lateral wall strain of RV (P<0.0001) and RV average global strain (P<0.0001) than controls. Regarding LV, they had lower LV end diastolic dimension (EDD, P<0.0001), LV end systolic dimension (P<0.003), E/A ratio (P<0.0001) and LV global longitudinal strain (GLS, P<0.028) than controls. BODE index had negative correlation with TAPSE (P<0.0001), LVEDD (P<0.022) and global RV strain (P<0.014). Significant differences were demonstrated among BODE quartiles regarding RV FAC%, TAPSE and RV average global strain. Significant differences were between BODE quartiles and controls regarding RV FAC%, TAPSE, RV lateral wall strain, RV average global strain, E/A ratio and LVEDD.
Conclusion COPD patients had RV, LV systolic dysfunction and LV diastolic dysfunction. The more COPD severity increased (assessed by BODE index) the more impairment of RV systolic function and LV diastolic function would be. |
| first_indexed | 2024-12-12T03:31:48Z |
| format | Article |
| id | doaj.art-d8ac49b37ce44c07b3aa11a267b2e135 |
| institution | Directory Open Access Journal |
| issn | 0422-7638 2090-9950 |
| language | English |
| last_indexed | 2024-12-12T03:31:48Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Egyptian Journal of Chest Disease and Tuberculosis |
| spelling | doaj.art-d8ac49b37ce44c07b3aa11a267b2e1352022-12-22T00:39:54ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382090-99502020-01-0169352453110.4103/ejcdt.ejcdt_168_19Study of the relation between speckle tracking echocardiography and BODE index in patients with chronic obstructive pulmonary diseaseOsama FahimAalaa FawziMorad BeshayMaha YousifBackground Chronic obstructive pulmonary disease (COPD) is a widespread lung disease with a high mortality and morbidity especially with co-morbid cardiac impairment. Severity of COPD can be assessed using BODE Index (body mass index, obstruction of airflow, dyspnea degree and exercise capacity). Aim To study the relationship between BODE index and right ventricle (RV) and left ventricle (LV) functions using Two-dimensional speckle-tracking echocardiography (2D-STE) in COPD patients. Subjects and methods Fifty stable COPD patients and matched fifty control subjects underwent transthoracic echocardiography, where conventional and speckle tracking parameters were taken. BODE indices were calculated and divided to quartiles (Q) (Q1; BODE index = 0–2, Q2; BODE index = 3–4 Q3; BODE index = 5–6, Q4; BODE index = 7–10). Results COPD patients had lower RV fractional area change (FAC%, P<0.0001), tricuspid annular plane systolic excursion (TAPSE, P<0.0001), lateral wall strain of RV (P<0.0001) and RV average global strain (P<0.0001) than controls. Regarding LV, they had lower LV end diastolic dimension (EDD, P<0.0001), LV end systolic dimension (P<0.003), E/A ratio (P<0.0001) and LV global longitudinal strain (GLS, P<0.028) than controls. BODE index had negative correlation with TAPSE (P<0.0001), LVEDD (P<0.022) and global RV strain (P<0.014). Significant differences were demonstrated among BODE quartiles regarding RV FAC%, TAPSE and RV average global strain. Significant differences were between BODE quartiles and controls regarding RV FAC%, TAPSE, RV lateral wall strain, RV average global strain, E/A ratio and LVEDD. Conclusion COPD patients had RV, LV systolic dysfunction and LV diastolic dysfunction. The more COPD severity increased (assessed by BODE index) the more impairment of RV systolic function and LV diastolic function would be.http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2020;volume=69;issue=3;spage=524;epage=531;aulast=Fahimbode indexchronic obstructive pulmonary diseasespeckle tracking echocardiography |
| spellingShingle | Osama Fahim Aalaa Fawzi Morad Beshay Maha Yousif Study of the relation between speckle tracking echocardiography and BODE index in patients with chronic obstructive pulmonary disease Egyptian Journal of Chest Disease and Tuberculosis bode index chronic obstructive pulmonary disease speckle tracking echocardiography |
| title | Study of the relation between speckle tracking echocardiography and BODE index in patients with chronic obstructive pulmonary disease |
| title_full | Study of the relation between speckle tracking echocardiography and BODE index in patients with chronic obstructive pulmonary disease |
| title_fullStr | Study of the relation between speckle tracking echocardiography and BODE index in patients with chronic obstructive pulmonary disease |
| title_full_unstemmed | Study of the relation between speckle tracking echocardiography and BODE index in patients with chronic obstructive pulmonary disease |
| title_short | Study of the relation between speckle tracking echocardiography and BODE index in patients with chronic obstructive pulmonary disease |
| title_sort | study of the relation between speckle tracking echocardiography and bode index in patients with chronic obstructive pulmonary disease |
| topic | bode index chronic obstructive pulmonary disease speckle tracking echocardiography |
| url | http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2020;volume=69;issue=3;spage=524;epage=531;aulast=Fahim |
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