DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program
BackgroundWhile adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary Approach to Stop Hypertension (DASH) food pattern...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-05-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.117.008089 |
| _version_ | 1811333970846023680 |
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| author | Luc Djoussé Yuk‐Lam Ho Xuan‐Mai T. Nguyen David R. Gagnon Peter W.F. Wilson Kelly Cho J. Michael Gaziano |
| author_facet | Luc Djoussé Yuk‐Lam Ho Xuan‐Mai T. Nguyen David R. Gagnon Peter W.F. Wilson Kelly Cho J. Michael Gaziano |
| author_sort | Luc Djoussé |
| collection | DOAJ |
| description | BackgroundWhile adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary Approach to Stop Hypertension (DASH) food pattern is associated with a lower risk of developing CAD among veterans. Methods and ResultsWe analyzed data on 153 802 participants of the Million Veteran Program enrolled between 2011 and 2016. Information on dietary habits was obtained using a food frequency questionnaire at enrollment. We used electronic health records to assess the development of CAD during follow‐up. Of the 153 802 veterans who provided information on diet and were free of CAD at baseline, the mean age was 64.0 (SD=11.8) years and 90.4% were men. During a mean follow‐up of 2.8 years, 5451 CAD cases occurred. The crude incidence rate of CAD was 14.0, 13.1, 12.6, 12.3, and 11.1 cases per 1000 person‐years across consecutive quintiles of Dietary Approach to Stop Hypertension score. Hazard ratios (95% confidence interval) for CAD were 1.0 (ref), 0.91 (0.84–0.99), 0.87 (0.80–0.95), 0.86 (0.79–0.94), and 0.80 (0.73–0.87) from the lowest to highest quintile of Dietary Approach to Stop Hypertension score controlling for age, sex, body mass index, race, smoking, exercise, alcohol intake, and statin use (P linear trend, <0.0001). ConclusionsOur data are consistent with an inverse association between Dietary Approach to Stop Hypertension diet score and incidence of CAD among US veterans. |
| first_indexed | 2024-04-13T17:00:43Z |
| format | Article |
| id | doaj.art-d8ad1b03770e45e290fbf6e9a4f70899 |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-04-13T17:00:43Z |
| publishDate | 2018-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-d8ad1b03770e45e290fbf6e9a4f708992022-12-22T02:38:40ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802018-05-017910.1161/JAHA.117.008089DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran ProgramLuc Djoussé0Yuk‐Lam Ho1Xuan‐Mai T. Nguyen2David R. Gagnon3Peter W.F. Wilson4Kelly Cho5J. Michael Gaziano6Massachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MAMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MAMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MAMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MAAtlanta VA Healthcare System and Emory School of Medicine, Atlanta, GAMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MAMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MABackgroundWhile adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary Approach to Stop Hypertension (DASH) food pattern is associated with a lower risk of developing CAD among veterans. Methods and ResultsWe analyzed data on 153 802 participants of the Million Veteran Program enrolled between 2011 and 2016. Information on dietary habits was obtained using a food frequency questionnaire at enrollment. We used electronic health records to assess the development of CAD during follow‐up. Of the 153 802 veterans who provided information on diet and were free of CAD at baseline, the mean age was 64.0 (SD=11.8) years and 90.4% were men. During a mean follow‐up of 2.8 years, 5451 CAD cases occurred. The crude incidence rate of CAD was 14.0, 13.1, 12.6, 12.3, and 11.1 cases per 1000 person‐years across consecutive quintiles of Dietary Approach to Stop Hypertension score. Hazard ratios (95% confidence interval) for CAD were 1.0 (ref), 0.91 (0.84–0.99), 0.87 (0.80–0.95), 0.86 (0.79–0.94), and 0.80 (0.73–0.87) from the lowest to highest quintile of Dietary Approach to Stop Hypertension score controlling for age, sex, body mass index, race, smoking, exercise, alcohol intake, and statin use (P linear trend, <0.0001). ConclusionsOur data are consistent with an inverse association between Dietary Approach to Stop Hypertension diet score and incidence of CAD among US veterans.https://www.ahajournals.org/doi/10.1161/JAHA.117.008089coronary artery diseaseepidemiologynutrition |
| spellingShingle | Luc Djoussé Yuk‐Lam Ho Xuan‐Mai T. Nguyen David R. Gagnon Peter W.F. Wilson Kelly Cho J. Michael Gaziano DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease coronary artery disease epidemiology nutrition |
| title | DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program |
| title_full | DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program |
| title_fullStr | DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program |
| title_full_unstemmed | DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program |
| title_short | DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program |
| title_sort | dash score and subsequent risk of coronary artery disease the findings from million veteran program |
| topic | coronary artery disease epidemiology nutrition |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.117.008089 |
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