Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids

Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids

Sublineages of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) Omicron variants continue to amass mutations in the spike (S) glycoprotein, which leads to immune evasion and rapid spread of the virus across the human population. Here we demonstrate the susceptibility of the Omicron varia...

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Bibliographic Details
Main Authors: Romain Volle, Luca Murer, Anthony Petkidis, Vardan Andriasyan, Alessandro Savi, Cornelia Bircher, Nicole Meili, Lucy Fischer, Daniela Policarpo Sequeira, Daniela Katharina Mark, Alfonso Gomez-Gonzalez, Urs F. Greber
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Microbial Sciences
Subjects:
SARS-CoV-2 variant of concern Omicron (BA.1)
Drug repurposing
Methylene blue
Mycophenolic acid
Posaconazole
Niclosamide
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517422000554

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