Alpha-Gal Syndrome: Involvement of Amblyomma americanum α-D-Galactosidase and β-1,4 Galactosyltransferase Enzymes in α-Gal Metabolism

Alpha-Gal Syndrome: Involvement of Amblyomma americanum α-D-Galactosidase and β-1,4 Galactosyltransferase Enzymes in α-Gal Metabolism

Alpha-Gal Syndrome (AGS) is an IgE-mediated delayed-type hypersensitivity reaction to the oligosaccharide galactose-α-1, 3-galactose (α-gal) injected into humans from the lone-star tick (Amblyomma americanum) bite. Indeed, α-gal is discovered in salivary glands of lone-star tick; however, the tick’s...

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Bibliographic Details
Main Authors:	Surendra Raj Sharma, Gary Crispell, Ahmed Mohamed, Cameron Cox, Joshua Lange, Shailesh Choudhary, Scott P. Commins, Shahid Karim
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-12-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	alpha-gal tick red meat allergy alpha-gal syndrome alpha-D-galactosidase beta-1
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2021.775371/full

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