Targeting the Immune System With Mesenchymal Stromal Cell-Derived Extracellular Vesicles: What Is the Cargo's Mechanism of Action?
The potent immunomodulatory activities displayed by mesenchymal stromal cells (MSCs) have motivated their application in hundreds of clinical trials to date. In some countries, they have subsequently been approved for the treatment of immune disorders such as Crohn's disease and graft-versus-ho...
Main Authors: | Jorge Diego Martin-Rufino, Natalia Espinosa-Lara, Lika Osugui, Fermin Sanchez-Guijo |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-11-01
|
Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2019.00308/full |
Similar Items
-
Therapeutic potential of mesenchymal stromal/stem cells in critical‐care patients with systemic inflammatory response syndrome
by: Gerardo‐Javier Martí‐Chillón, et al.
Published: (2023-01-01) -
Improving the therapeutic profile of MSCs: Cytokine priming reduces donor-dependent heterogeneity and enhances their immunomodulatory capacity
by: Jaris Valencia, et al.
Published: (2025-02-01) -
Extracellular vesicles from senescent mesenchymal stromal cells are defective and cannot prevent osteoarthritis
by: Jérémy Boulestreau, et al.
Published: (2024-05-01) -
Deciphering Master Gene Regulators and Associated Networks of Human Mesenchymal Stromal Cells
by: Elena Sánchez-Luis, et al.
Published: (2020-04-01) -
Autologous mesenchymal stromal cells embedded with Tissucol Duo® for prevention of air leak after anatomical lung resection: results of a prospective phase I/II clinical trial with long-term follow-up
by: Marcelo F. Jiménez, et al.
Published: (2023-10-01)