Castration promotes the browning of the prostate tumor microenvironment

Castration promotes the browning of the prostate tumor microenvironment

Abstract Background Adipose tissue has gained attention due to its potential paracrine role. Periprostatic adipose tissue surrounds the prostate and the prostatic urethra, and it is an essential player in prostate cancer progression. Since obesity is directly related to human tumor progression, and...

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Bibliographic Details
Main Authors: Alejandro Alvarez-Artime, Belen Garcia-Soler, Pedro Gonzalez-Menendez, Sheila Fernandez-Vega, Rafael Cernuda-Cernuda, David Hevia, Juan C. Mayo, Rosa M. Sainz
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cell Communication and Signaling
Subjects:
Prostate cancer
Browning
Adipose tissue
Tumor microenvironment
UCP1
Online Access:https://doi.org/10.1186/s12964-023-01294-y

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