Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain)
<p>Abstract</p> <p>Background</p> <p>Community-acquired pneumonia (CAP) has large impact on direct healthcare costs, especially those derived from hospitalization. This study determines impact, clinical characteristics, outcome and economic consequences of CAP in the ad...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-11-01
|
| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1471-2334/12/283 |
| _version_ | 1811282354679840768 |
|---|---|
| author | Sicras-Mainar Antoni Ibáñez-Nolla Jordi Cifuentes Isabel Guijarro Pablo Navarro-Artieda Ruth Aguilar Lorenzo |
| author_facet | Sicras-Mainar Antoni Ibáñez-Nolla Jordi Cifuentes Isabel Guijarro Pablo Navarro-Artieda Ruth Aguilar Lorenzo |
| author_sort | Sicras-Mainar Antoni |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Community-acquired pneumonia (CAP) has large impact on direct healthcare costs, especially those derived from hospitalization. This study determines impact, clinical characteristics, outcome and economic consequences of CAP in the adult (≥18 years) population attended in 6 primary-care centers and 2 hospitals in Badalona (Spain) over a two-year period.</p> <p>Methods</p> <p>Medical records were identified by codes from the International Classification of Diseases in databases (January 1<sup>st</sup> 2008-December 31<sup>st</sup> 2009).</p> <p>Results</p> <p>A total of 581 patients with CAP (55.6% males, mean age 57.5 years) were identified. Prevalence: 0.64% (95% CI: 0.5%-0.7%); annual incidence: 3.0 cases/1,000 inhabitants (95% CI: 0.2-0.5). Up to 241 (41.5%) required hospitalization. Hospital admission was associated (p<0.002) with liver disease (OR=5.9), stroke (OR=3.6), dementia (OR=3.5), COPD (OR=2.9), diabetes mellitus (OR=1.9) and age (OR=1.1 per year). Length of stay (4.4±0.3 days) was associated with PSI score (β=0.195), in turn associated with age (r=0.827) and Charlson index (r=0.497). Microbiological tests were performed in all inpatients but only in 35% outpatients. Among patients with microbiological tests, results were positive in 51.7%, and among them, <it>S pneumoniae</it> was identified in 57.5% cases. Time to recovery was 29.9±17.2 days. Up to 7.5% inpatients presented complications, 0.8% required ICU admission and 19.1% readmission. Inhospital mortality rate was 2.5%. Adjusted mean total cost was €2,332.4/inpatient and €698.6/outpatient (p<0.001). Patients with pneumococcal CAP (n=107) showed higher comorbidity and hospitalization (76.6%), higher PSI score, larger time to recovery and higher overall costs among inpatients.</p> <p>Conclusions</p> <p>Strategies preventing CAP, thus reducing hospital admissions could likely produce substantial costs savings in addition to the reduction of CAP burden.</p> |
| first_indexed | 2024-04-13T01:51:11Z |
| format | Article |
| id | doaj.art-d8b69628df334bf0b251e4db211b7d81 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-13T01:51:11Z |
| publishDate | 2012-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-d8b69628df334bf0b251e4db211b7d812022-12-22T03:07:53ZengBMCBMC Infectious Diseases1471-23342012-11-0112128310.1186/1471-2334-12-283Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain)Sicras-Mainar AntoniIbáñez-Nolla JordiCifuentes IsabelGuijarro PabloNavarro-Artieda RuthAguilar Lorenzo<p>Abstract</p> <p>Background</p> <p>Community-acquired pneumonia (CAP) has large impact on direct healthcare costs, especially those derived from hospitalization. This study determines impact, clinical characteristics, outcome and economic consequences of CAP in the adult (≥18 years) population attended in 6 primary-care centers and 2 hospitals in Badalona (Spain) over a two-year period.</p> <p>Methods</p> <p>Medical records were identified by codes from the International Classification of Diseases in databases (January 1<sup>st</sup> 2008-December 31<sup>st</sup> 2009).</p> <p>Results</p> <p>A total of 581 patients with CAP (55.6% males, mean age 57.5 years) were identified. Prevalence: 0.64% (95% CI: 0.5%-0.7%); annual incidence: 3.0 cases/1,000 inhabitants (95% CI: 0.2-0.5). Up to 241 (41.5%) required hospitalization. Hospital admission was associated (p<0.002) with liver disease (OR=5.9), stroke (OR=3.6), dementia (OR=3.5), COPD (OR=2.9), diabetes mellitus (OR=1.9) and age (OR=1.1 per year). Length of stay (4.4±0.3 days) was associated with PSI score (β=0.195), in turn associated with age (r=0.827) and Charlson index (r=0.497). Microbiological tests were performed in all inpatients but only in 35% outpatients. Among patients with microbiological tests, results were positive in 51.7%, and among them, <it>S pneumoniae</it> was identified in 57.5% cases. Time to recovery was 29.9±17.2 days. Up to 7.5% inpatients presented complications, 0.8% required ICU admission and 19.1% readmission. Inhospital mortality rate was 2.5%. Adjusted mean total cost was €2,332.4/inpatient and €698.6/outpatient (p<0.001). Patients with pneumococcal CAP (n=107) showed higher comorbidity and hospitalization (76.6%), higher PSI score, larger time to recovery and higher overall costs among inpatients.</p> <p>Conclusions</p> <p>Strategies preventing CAP, thus reducing hospital admissions could likely produce substantial costs savings in addition to the reduction of CAP burden.</p>http://www.biomedcentral.com/1471-2334/12/283Community-acquired pneumonia<it>Streptococcus pneumoniae</it>Primary care settingHospital settingResource utilizationHealth costs |
| spellingShingle | Sicras-Mainar Antoni Ibáñez-Nolla Jordi Cifuentes Isabel Guijarro Pablo Navarro-Artieda Ruth Aguilar Lorenzo Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain) BMC Infectious Diseases Community-acquired pneumonia <it>Streptococcus pneumoniae</it> Primary care setting Hospital setting Resource utilization Health costs |
| title | Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain) |
| title_full | Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain) |
| title_fullStr | Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain) |
| title_full_unstemmed | Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain) |
| title_short | Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain) |
| title_sort | retrospective epidemiological study for the characterization of community acquired pneumonia and pneumococcal pneumonia in adults in a well defined area of badalona barcelona spain |
| topic | Community-acquired pneumonia <it>Streptococcus pneumoniae</it> Primary care setting Hospital setting Resource utilization Health costs |
| url | http://www.biomedcentral.com/1471-2334/12/283 |
| work_keys_str_mv | AT sicrasmainarantoni retrospectiveepidemiologicalstudyforthecharacterizationofcommunityacquiredpneumoniaandpneumococcalpneumoniainadultsinawelldefinedareaofbadalonabarcelonaspain AT ibaneznollajordi retrospectiveepidemiologicalstudyforthecharacterizationofcommunityacquiredpneumoniaandpneumococcalpneumoniainadultsinawelldefinedareaofbadalonabarcelonaspain AT cifuentesisabel retrospectiveepidemiologicalstudyforthecharacterizationofcommunityacquiredpneumoniaandpneumococcalpneumoniainadultsinawelldefinedareaofbadalonabarcelonaspain AT guijarropablo retrospectiveepidemiologicalstudyforthecharacterizationofcommunityacquiredpneumoniaandpneumococcalpneumoniainadultsinawelldefinedareaofbadalonabarcelonaspain AT navarroartiedaruth retrospectiveepidemiologicalstudyforthecharacterizationofcommunityacquiredpneumoniaandpneumococcalpneumoniainadultsinawelldefinedareaofbadalonabarcelonaspain AT aguilarlorenzo retrospectiveepidemiologicalstudyforthecharacterizationofcommunityacquiredpneumoniaandpneumococcalpneumoniainadultsinawelldefinedareaofbadalonabarcelonaspain |