Comparison of Tendon Development Versus Tendon Healing and Regeneration
Tendon is a vital connective tissue in human skeletal muscle system, and tendon injury is very common and intractable in clinic. Tendon development and repair are two closely related but still not fully understood processes. Tendon development involves multiple germ layer, as well as the regulation...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-01-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2022.821667/full |
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| author | Peiwen He Peiwen He Peiwen He Peiwen He Dengfeng Ruan Dengfeng Ruan Dengfeng Ruan Zizhan Huang Zizhan Huang Zizhan Huang Canlong Wang Canlong Wang Canlong Wang Yiwen Xu Yiwen Xu Yiwen Xu Honglu Cai Honglu Cai Honglu Cai Hengzhi Liu Hengzhi Liu Hengzhi Liu Yang Fei Yang Fei Yang Fei Boon Chin Heng Weishan Chen Weishan Chen Weishan Chen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen |
| author_facet | Peiwen He Peiwen He Peiwen He Peiwen He Dengfeng Ruan Dengfeng Ruan Dengfeng Ruan Zizhan Huang Zizhan Huang Zizhan Huang Canlong Wang Canlong Wang Canlong Wang Yiwen Xu Yiwen Xu Yiwen Xu Honglu Cai Honglu Cai Honglu Cai Hengzhi Liu Hengzhi Liu Hengzhi Liu Yang Fei Yang Fei Yang Fei Boon Chin Heng Weishan Chen Weishan Chen Weishan Chen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen |
| author_sort | Peiwen He |
| collection | DOAJ |
| description | Tendon is a vital connective tissue in human skeletal muscle system, and tendon injury is very common and intractable in clinic. Tendon development and repair are two closely related but still not fully understood processes. Tendon development involves multiple germ layer, as well as the regulation of diversity transcription factors (Scx et al.), proteins (Tnmd et al.) and signaling pathways (TGFβ et al.). The nature process of tendon repair is roughly divided in three stages, which are dominated by various cells and cell factors. This review will describe the whole process of tendon development and compare it with the process of tendon repair, focusing on the understanding and recent advances in the regulation of tendon development and repair. The study and comparison of tendon development and repair process can thus provide references and guidelines for treatment of tendon injuries. |
| first_indexed | 2024-12-20T16:10:45Z |
| format | Article |
| id | doaj.art-d8b91929b9514dca82074947e7b36cd7 |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-12-20T16:10:45Z |
| publishDate | 2022-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-d8b91929b9514dca82074947e7b36cd72022-12-21T19:33:59ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2022-01-011010.3389/fcell.2022.821667821667Comparison of Tendon Development Versus Tendon Healing and RegenerationPeiwen He0Peiwen He1Peiwen He2Peiwen He3Dengfeng Ruan4Dengfeng Ruan5Dengfeng Ruan6Zizhan Huang7Zizhan Huang8Zizhan Huang9Canlong Wang10Canlong Wang11Canlong Wang12Yiwen Xu13Yiwen Xu14Yiwen Xu15Honglu Cai16Honglu Cai17Honglu Cai18Hengzhi Liu19Hengzhi Liu20Hengzhi Liu21Yang Fei22Yang Fei23Yang Fei24Boon Chin Heng25Weishan Chen26Weishan Chen27Weishan Chen28Weiliang Shen29Weiliang Shen30Weiliang Shen31Weiliang Shen32Weiliang Shen33Weiliang Shen34Department of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaCentral Laboratory, Peking University School of Stomatology, Bejing, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaOrthopedics Research Institute of Zhejiang University, Hangzhou, ChinaInstitute of Sports Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou, ChinaDr. Li Dak Sum and Yip Yio Chin Center for Stem Cell and Regenerative Medicine, Zhejiang University, Hangzhou, ChinaChina Orthopaedic Regenerative Medicine (CORMed), Hangzhou, ChinaTendon is a vital connective tissue in human skeletal muscle system, and tendon injury is very common and intractable in clinic. Tendon development and repair are two closely related but still not fully understood processes. Tendon development involves multiple germ layer, as well as the regulation of diversity transcription factors (Scx et al.), proteins (Tnmd et al.) and signaling pathways (TGFβ et al.). The nature process of tendon repair is roughly divided in three stages, which are dominated by various cells and cell factors. This review will describe the whole process of tendon development and compare it with the process of tendon repair, focusing on the understanding and recent advances in the regulation of tendon development and repair. The study and comparison of tendon development and repair process can thus provide references and guidelines for treatment of tendon injuries.https://www.frontiersin.org/articles/10.3389/fcell.2022.821667/fulltendondevelopmenthealingregenerationregulationcomparison |
| spellingShingle | Peiwen He Peiwen He Peiwen He Peiwen He Dengfeng Ruan Dengfeng Ruan Dengfeng Ruan Zizhan Huang Zizhan Huang Zizhan Huang Canlong Wang Canlong Wang Canlong Wang Yiwen Xu Yiwen Xu Yiwen Xu Honglu Cai Honglu Cai Honglu Cai Hengzhi Liu Hengzhi Liu Hengzhi Liu Yang Fei Yang Fei Yang Fei Boon Chin Heng Weishan Chen Weishan Chen Weishan Chen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen Weiliang Shen Comparison of Tendon Development Versus Tendon Healing and Regeneration Frontiers in Cell and Developmental Biology tendon development healing regeneration regulation comparison |
| title | Comparison of Tendon Development Versus Tendon Healing and Regeneration |
| title_full | Comparison of Tendon Development Versus Tendon Healing and Regeneration |
| title_fullStr | Comparison of Tendon Development Versus Tendon Healing and Regeneration |
| title_full_unstemmed | Comparison of Tendon Development Versus Tendon Healing and Regeneration |
| title_short | Comparison of Tendon Development Versus Tendon Healing and Regeneration |
| title_sort | comparison of tendon development versus tendon healing and regeneration |
| topic | tendon development healing regeneration regulation comparison |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2022.821667/full |
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