Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave Lithotripsy

Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave Lithotripsy

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Main Authors: Hooman Djaladat, Khatereh Mahouri, Fatemeh Khalifeh Shooshtary, Azadeh Ahmadieh
Format: Article
Language:English
Published: Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences 2009-02-01
Series:Urology Journal
Online Access:http://www.urologyjournal.org/index.php/uj/article/view/80
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author Hooman Djaladat
Khatereh Mahouri
Fatemeh Khalifeh Shooshtary
Azadeh Ahmadieh
author_facet Hooman Djaladat
Khatereh Mahouri
Fatemeh Khalifeh Shooshtary
Azadeh Ahmadieh
author_sort Hooman Djaladat
collection DOAJ
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 </style> <![endif]--> <p class="MsoNormal" style="margin-right: -0.85pt; text-align: left; direction: ltr; unicode-bidi: embed;"><strong>Introduction: </strong>our aim was to evaluate the effect of Rowatinex, an essential oil preparation of terpenic type, on kidney calculi clearance after extracorporeal shock wave lithotripsy (SWL).</p> <p class="MsoNormal" style="margin-right: -0.85pt; text-align: left; direction: ltr; unicode-bidi: embed;"><strong>Materials and Methods: </strong>A randomized controlled trial was performed at Hormozgan Hospital in Bandar Abbas, Iran, on 100 patients with 10-mm to 20-mm kidney calculi. They underwent SWL, and then, they were randomly assigned into 2 groups to receive either Rowatinex, 100 mg, 3 times per day, or placebo after SWL. Patients were followed up with plain abdominal radiography, ultrasonography, and excretory urography (if required), 2 and 4 weeks postoperatively.</p> <p class="MsoNormal" style="margin-right: -0.85pt; text-align: left; direction: ltr; unicode-bidi: embed;"><strong>Results:</strong> Two weeks following SWL, 6 (12%) and 9 (18%) patients in the Rowatinex and control groups had fragmented calculi without clearance, 26 (52%) and 24 (48%) had less than 50% clearance, 9 (18%) and 15 (30%) had more than 50% but not total clearance, and 9 (18%) and 2 (4%) patients were stone free, respectively. Rowatinex had a significant effect on the stone-free rate (<em>P </em>= .02). Four weeks post-SWL, 3 (7.3%) and 7 (14.6%) other patients in the Rowatinex and control groups became stone free, respectively. Overall, Rowatinex had no significant effect on the stone-free rate (<em>P </em>= .46). No complications or differences between the two groups in symptoms and signs were reported.</p> <p class="MsoNormal" style="text-align: left; direction: ltr; unicode-bidi: embed;"><strong>Conclusion: </strong>Rowatinex does not have a significant effect on clearance rate of kidney calculi after SWL. However, it can accelerate calculus passage after 2 weeks, and it does not have any significant adverse effects.</p>
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spelling doaj.art-d8b9f9cb6ebe45398d29512a602fe9112022-12-21T23:35:15ZengUrology and Nephrology Research Center, Shahid Beheshti University of Medical SciencesUrology Journal1735-13081735-546X2009-02-0161913Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave LithotripsyHooman DjaladatKhatereh MahouriFatemeh Khalifeh ShooshtaryAzadeh Ahmadieh<!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> </w:WordDocument> </xml><![endif]--><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState="false" LatentStyleCount="156"> </w:LatentStyles> </xml><![endif]--><!--[if !mso]><object classid="clsid:38481807-CA0E-42D2-BF39-B33AF135CC4D" id=ieooui></object> <style>
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 </style> <![endif]--> <p class="MsoNormal" style="margin-right: -0.85pt; text-align: left; direction: ltr; unicode-bidi: embed;"><strong>Introduction: </strong>our aim was to evaluate the effect of Rowatinex, an essential oil preparation of terpenic type, on kidney calculi clearance after extracorporeal shock wave lithotripsy (SWL).</p> <p class="MsoNormal" style="margin-right: -0.85pt; text-align: left; direction: ltr; unicode-bidi: embed;"><strong>Materials and Methods: </strong>A randomized controlled trial was performed at Hormozgan Hospital in Bandar Abbas, Iran, on 100 patients with 10-mm to 20-mm kidney calculi. They underwent SWL, and then, they were randomly assigned into 2 groups to receive either Rowatinex, 100 mg, 3 times per day, or placebo after SWL. Patients were followed up with plain abdominal radiography, ultrasonography, and excretory urography (if required), 2 and 4 weeks postoperatively.</p> <p class="MsoNormal" style="margin-right: -0.85pt; text-align: left; direction: ltr; unicode-bidi: embed;"><strong>Results:</strong> Two weeks following SWL, 6 (12%) and 9 (18%) patients in the Rowatinex and control groups had fragmented calculi without clearance, 26 (52%) and 24 (48%) had less than 50% clearance, 9 (18%) and 15 (30%) had more than 50% but not total clearance, and 9 (18%) and 2 (4%) patients were stone free, respectively. Rowatinex had a significant effect on the stone-free rate (<em>P </em>= .02). Four weeks post-SWL, 3 (7.3%) and 7 (14.6%) other patients in the Rowatinex and control groups became stone free, respectively. Overall, Rowatinex had no significant effect on the stone-free rate (<em>P </em>= .46). No complications or differences between the two groups in symptoms and signs were reported.</p> <p class="MsoNormal" style="text-align: left; direction: ltr; unicode-bidi: embed;"><strong>Conclusion: </strong>Rowatinex does not have a significant effect on clearance rate of kidney calculi after SWL. However, it can accelerate calculus passage after 2 weeks, and it does not have any significant adverse effects.</p>http://www.urologyjournal.org/index.php/uj/article/view/80
spellingShingle Hooman Djaladat
Khatereh Mahouri
Fatemeh Khalifeh Shooshtary
Azadeh Ahmadieh
Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave Lithotripsy
Urology Journal
title Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave Lithotripsy
title_full Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave Lithotripsy
title_fullStr Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave Lithotripsy
title_full_unstemmed Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave Lithotripsy
title_short Effect of Rowatinex on Calculus Clearance After Extracorporeal Shock Wave Lithotripsy
title_sort effect of rowatinex on calculus clearance after extracorporeal shock wave lithotripsy
url http://www.urologyjournal.org/index.php/uj/article/view/80
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AT khaterehmahouri effectofrowatinexoncalculusclearanceafterextracorporealshockwavelithotripsy
AT fatemehkhalifehshooshtary effectofrowatinexoncalculusclearanceafterextracorporealshockwavelithotripsy
AT azadehahmadieh effectofrowatinexoncalculusclearanceafterextracorporealshockwavelithotripsy

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