Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2017-07-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/browse.php?a_code=A-10-605-1&slc_lang=en&sid=1 |
| _version_ | 1819181746242977792 |
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| author | Ehsan Saburi Amin Saburi Mostafa Ghanei |
| author_facet | Ehsan Saburi Amin Saburi Mostafa Ghanei |
| author_sort | Ehsan Saburi |
| collection | DOAJ |
| description | Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications can also enhance immune-cell activity against tumors. Such medications show great potential in cancer immunotherapy using natural human mechanisms against neoplasms. |
| first_indexed | 2024-12-22T22:35:08Z |
| format | Article |
| id | doaj.art-d8ba315e94354eeebcc7458fd4939b04 |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-12-22T22:35:08Z |
| publishDate | 2017-07-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-d8ba315e94354eeebcc7458fd4939b042022-12-21T18:10:20ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722017-07-0184228238Promising role for Gc-MAF in cancer immunotherapy: from bench to bedsideEhsan Saburi0Amin Saburi1Mostafa Ghanei2 Molecular Medicine Department, Zanjan University of medical Sciences, Zanjan, Iran. Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications can also enhance immune-cell activity against tumors. Such medications show great potential in cancer immunotherapy using natural human mechanisms against neoplasms.http://caspjim.com/browse.php?a_code=A-10-605-1&slc_lang=en&sid=1Cancer Immunotherapy Macrophage activating factor GC-MAF Vitamin D. |
| spellingShingle | Ehsan Saburi Amin Saburi Mostafa Ghanei Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside Caspian Journal of Internal Medicine Cancer Immunotherapy Macrophage activating factor GC-MAF Vitamin D. |
| title | Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside |
| title_full | Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside |
| title_fullStr | Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside |
| title_full_unstemmed | Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside |
| title_short | Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside |
| title_sort | promising role for gc maf in cancer immunotherapy from bench to bedside |
| topic | Cancer Immunotherapy Macrophage activating factor GC-MAF Vitamin D. |
| url | http://caspjim.com/browse.php?a_code=A-10-605-1&slc_lang=en&sid=1 |
| work_keys_str_mv | AT ehsansaburi promisingroleforgcmafincancerimmunotherapyfrombenchtobedside AT aminsaburi promisingroleforgcmafincancerimmunotherapyfrombenchtobedside AT mostafaghanei promisingroleforgcmafincancerimmunotherapyfrombenchtobedside |