IMPACT OF GENDER AND AGE ON IN-HOSPITAL OUTCOMES OF CORONARY ARTERY BYPASS GRAFTING

Aim. To evaluate the impact of age and gender on in-hospital outcomes of coronary artery bypass grafting (CABG) in patients with coronary artery disease. Methods. 538 (79.10 %) men and 142 (20.90 %) women ( n = = 680) in the CABG registry of the Research Institute for Complex Issues of Cardiovascula...

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Main Authors: I. I. Zhidkova, I. A. Shibanova, S. V. Ivanov, A. N. Sumin, O. L. Barbarash, I. V. Samorodskaya
Format: Article
Language:Russian
Published: Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics 2018-12-01
Series:Атеросклероз
Subjects:
Online Access:https://ateroskleroz.elpub.ru/jour/article/view/88/88
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author I. I. Zhidkova
I. A. Shibanova
S. V. Ivanov
A. N. Sumin
O. L. Barbarash
I. V. Samorodskaya
author_facet I. I. Zhidkova
I. A. Shibanova
S. V. Ivanov
A. N. Sumin
O. L. Barbarash
I. V. Samorodskaya
author_sort I. I. Zhidkova
collection DOAJ
description Aim. To evaluate the impact of age and gender on in-hospital outcomes of coronary artery bypass grafting (CABG) in patients with coronary artery disease. Methods. 538 (79.10 %) men and 142 (20.90 %) women ( n = = 680) in the CABG registry of the Research Institute for Complex Issues of Cardiovascular who were referred to CABG in the period from 2011 to 2012 were retrospectively reviewed to assess the prevalence of comorbidities and estimate the in-hospital outcomes. The mean age of patients was 59.12 ± 7.98 (33 to 78 years). All patients were assigned to 4 age groups: Group 1 - <50 years, Group 2 - 51-60 years, Group 3 - 61-70 years, Group 4 - >70 years. The statistical analysis was performed using the software package SPSS 20.0.1. A p value of <0.05 was considered statistically significant. Results. Women were commonly older than men and had a positive history of hypertension, chronic heart failure and higher angina class, obesity, type 2 diabetes, impaired glucose tolerance, non-ulcerative lesions of the gastrointestinal (GI) tract (gastritis, cholecystitis and / or pancreatitis). The male group was superior to the female group in the number of smokers and prior myocardial infarction. The incidence of first detected atrial fibrillation, atrial flutter, as well as ischemic strokes, congestive pneumonia increased with aging in both men and women within the in-hospital period. However, women, particularly from the younger age group (<50 years), more frequently suffered from ischemic strokes, GI bleedings, exacerbation of erosive gastritis, compared with men. Women from the older age group commonly had hydrothorax requiring pleural puncture, surgical wound healing complications, and exacerbation or / the first detected duodenal and / or stomach ulcers, compared to men. Conclusion: Female gender is associated with a significantly higher rate of the in-hospital complications compared to men. However, the impact of gender is mediated by age differences between men and women undergoing CABG.
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spelling doaj.art-d8c5bfb87221414aa9b7a97e283f0ca62023-01-03T02:14:13ZrusSiberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and GeneticsАтеросклероз2078-256X2018-12-011441424https://doi.org/10.15372/ATER20180402IMPACT OF GENDER AND AGE ON IN-HOSPITAL OUTCOMES OF CORONARY ARTERY BYPASS GRAFTINGI. I. Zhidkova0I. A. Shibanova1S. V. Ivanov2A. N. Sumin3O. L. Barbarash4I. V. Samorodskaya5Scientific Research Institute for Complex Issues of Cardiovascular Diseases Russian FederationKemerovo Regional Clinical Cardiological Clinic Named after Academician L.S. Barbarash Russian FederationScientific Research Institute for Complex Issues of Cardiovascular Diseases Russian FederationScientific Research Institute for Complex Issues of Cardiovascular Diseases Russian FederationScientific Research Institute for Complex Issues of Cardiovascular Diseases Russian FederationState Research Center for Preventive Medicine of the Ministry of Health of Russia Russian FederationAim. To evaluate the impact of age and gender on in-hospital outcomes of coronary artery bypass grafting (CABG) in patients with coronary artery disease. Methods. 538 (79.10 %) men and 142 (20.90 %) women ( n = = 680) in the CABG registry of the Research Institute for Complex Issues of Cardiovascular who were referred to CABG in the period from 2011 to 2012 were retrospectively reviewed to assess the prevalence of comorbidities and estimate the in-hospital outcomes. The mean age of patients was 59.12 ± 7.98 (33 to 78 years). All patients were assigned to 4 age groups: Group 1 - <50 years, Group 2 - 51-60 years, Group 3 - 61-70 years, Group 4 - >70 years. The statistical analysis was performed using the software package SPSS 20.0.1. A p value of <0.05 was considered statistically significant. Results. Women were commonly older than men and had a positive history of hypertension, chronic heart failure and higher angina class, obesity, type 2 diabetes, impaired glucose tolerance, non-ulcerative lesions of the gastrointestinal (GI) tract (gastritis, cholecystitis and / or pancreatitis). The male group was superior to the female group in the number of smokers and prior myocardial infarction. The incidence of first detected atrial fibrillation, atrial flutter, as well as ischemic strokes, congestive pneumonia increased with aging in both men and women within the in-hospital period. However, women, particularly from the younger age group (<50 years), more frequently suffered from ischemic strokes, GI bleedings, exacerbation of erosive gastritis, compared with men. Women from the older age group commonly had hydrothorax requiring pleural puncture, surgical wound healing complications, and exacerbation or / the first detected duodenal and / or stomach ulcers, compared to men. Conclusion: Female gender is associated with a significantly higher rate of the in-hospital complications compared to men. However, the impact of gender is mediated by age differences between men and women undergoing CABG.https://ateroskleroz.elpub.ru/jour/article/view/88/88coronary artery bypass graftingage and gender characteristicshospital complicationscombined outcome
spellingShingle I. I. Zhidkova
I. A. Shibanova
S. V. Ivanov
A. N. Sumin
O. L. Barbarash
I. V. Samorodskaya
IMPACT OF GENDER AND AGE ON IN-HOSPITAL OUTCOMES OF CORONARY ARTERY BYPASS GRAFTING
Атеросклероз
coronary artery bypass grafting
age and gender characteristics
hospital complications
combined outcome
title IMPACT OF GENDER AND AGE ON IN-HOSPITAL OUTCOMES OF CORONARY ARTERY BYPASS GRAFTING
title_full IMPACT OF GENDER AND AGE ON IN-HOSPITAL OUTCOMES OF CORONARY ARTERY BYPASS GRAFTING
title_fullStr IMPACT OF GENDER AND AGE ON IN-HOSPITAL OUTCOMES OF CORONARY ARTERY BYPASS GRAFTING
title_full_unstemmed IMPACT OF GENDER AND AGE ON IN-HOSPITAL OUTCOMES OF CORONARY ARTERY BYPASS GRAFTING
title_short IMPACT OF GENDER AND AGE ON IN-HOSPITAL OUTCOMES OF CORONARY ARTERY BYPASS GRAFTING
title_sort impact of gender and age on in hospital outcomes of coronary artery bypass grafting
topic coronary artery bypass grafting
age and gender characteristics
hospital complications
combined outcome
url https://ateroskleroz.elpub.ru/jour/article/view/88/88
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AT svivanov impactofgenderandageoninhospitaloutcomesofcoronaryarterybypassgrafting
AT ansumin impactofgenderandageoninhospitaloutcomesofcoronaryarterybypassgrafting
AT olbarbarash impactofgenderandageoninhospitaloutcomesofcoronaryarterybypassgrafting
AT ivsamorodskaya impactofgenderandageoninhospitaloutcomesofcoronaryarterybypassgrafting