Evaluation of the Anti-Inflammatory Effect of Chalcone and Chalcone Analogues in a Zebrafish Model
The aim of this study was to investigate novel chalcones with potent anti-inflammatory activities in vivo. Chalcone and two chalcone analogues (compound 5 and 9) were evaluated using a caudal fin-wounded transgenic zebrafish line “Tg(mpx:gfp)” to visualize the effect of neutrophil recruitment dynami...
Main Authors: | Chi-Chung Wen, Zi-Yu Lin, Yun-Hsin Wang, Wei-Hua Wang, Yau-Hung Chen, Ching-Yuh Chern |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-02-01
|
Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/18/2/2052 |
Similar Items
-
Toxicity Assessments of Chalcone and Some Synthetic Chalcone Analogues in a Zebrafish Model
by: Ya-Ting Lee, et al.
Published: (2014-01-01) -
Pro-Angiogenic Effects of Chalcone Derivatives in Zebrafish Embryos in Vivo
by: Yau-Hung Chen, et al.
Published: (2015-07-01) -
Synthesis of New AIEE-Active Chalcones for Imaging of Mitochondria in Living Cells and Zebrafish In Vivo
by: Huiqing Luo, et al.
Published: (2021-08-01) -
In silico studies, X-ray diffraction analysis and biological investigation of fluorinated pyrrolylated-chalcones in zebrafish epilepsy models
by: Muhammad Syafiq Akmal Mohd Fahmi, et al.
Published: (2023-02-01) -
Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors
by: Moran Sun, et al.
Published: (2022-12-01)