A Subset of Nuclear Receptors Are Uniquely Expressed in Uveal Melanoma Cells

A Subset of Nuclear Receptors Are Uniquely Expressed in Uveal Melanoma Cells

Uveal melanoma (UM) is recognized as the most common intraocular malignancy and the second most common form of melanoma. Nearly 50% of UM patients develop untreatable and fatal metastases. The 48-member nuclear receptor (NR) superfamily represents a therapeutically targetable group of transcriptio...

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Bibliographic Details
Main Authors: Kenneth Edward Huffman, Ryan eCarstens, Elisabeth D Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Endocrinology
Subjects:
Uveal Melanoma
cutaneous melanoma
profiling
NCI-60
Nuclear receptor expression
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00093/full

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