Assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients: An In vivo study

Aims: To assess the salivary flow rate levels and total antioxidant levels in ectodermal dysplasia (ED) patients and to compare with normal individuals. Materials and Methods: Unstimulated saliva sample of control and case were collected from the mouth to a pre-weighed Eppendorf tube using a Pasteur...

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Main Authors: Aravind Mohanan, Balagopal R Varma, Suresh Kumar, Parvathy Kumaran, Arun Mamachan Xavier
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Contemporary Clinical Dentistry
Subjects:
Online Access:http://www.contempclindent.org/article.asp?issn=0976-237X;year=2019;volume=10;issue=1;spage=74;epage=80;aulast=Mohanan
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author Aravind Mohanan
Balagopal R Varma
Suresh Kumar
Parvathy Kumaran
Arun Mamachan Xavier
author_facet Aravind Mohanan
Balagopal R Varma
Suresh Kumar
Parvathy Kumaran
Arun Mamachan Xavier
author_sort Aravind Mohanan
collection DOAJ
description Aims: To assess the salivary flow rate levels and total antioxidant levels in ectodermal dysplasia (ED) patients and to compare with normal individuals. Materials and Methods: Unstimulated saliva sample of control and case were collected from the mouth to a pre-weighed Eppendorf tube using a Pasteur pipette for 4 min. Stimulated saliva of case and control was also collected after chewing paraffin wax for 30 s. Both the Eppendorf tubes were weighed again after collection of both the saliva samples. The flow rate was calculated as difference of weight of the tube divided by time (4 min). Both unstimulated and stimulated saliva was also separately collected for estimation for total antioxidant levels. Statistical analysis: For intergroup comparison, Mann–Whitney test was used, and for intragroup comparison, Wilcoxon signed-rank test was used. Results: In the intergroup comparison of both the salivary flow rate and total antioxidant levels, there was no statistically significant difference; however, there was statistically significant difference in the intragroup comparison of salivary flow rate and total antioxidant levels in case group. Conclusions: There was a diminished unstimulated salivary flow rate in ED group, but stimulated salivary flow rate was significantly high and the total antioxidant levels in unstimulated saliva of the case group were significantly higher than the stimulated antioxidant levels.
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spelling doaj.art-d8d1282c4e3d44d397df9a4e02b8c33e2022-12-21T18:45:40ZengWolters Kluwer Medknow PublicationsContemporary Clinical Dentistry0976-237X0976-23612019-01-01101748010.4103/ccd.ccd_358_18Assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients: An In vivo studyAravind MohananBalagopal R VarmaSuresh KumarParvathy KumaranArun Mamachan XavierAims: To assess the salivary flow rate levels and total antioxidant levels in ectodermal dysplasia (ED) patients and to compare with normal individuals. Materials and Methods: Unstimulated saliva sample of control and case were collected from the mouth to a pre-weighed Eppendorf tube using a Pasteur pipette for 4 min. Stimulated saliva of case and control was also collected after chewing paraffin wax for 30 s. Both the Eppendorf tubes were weighed again after collection of both the saliva samples. The flow rate was calculated as difference of weight of the tube divided by time (4 min). Both unstimulated and stimulated saliva was also separately collected for estimation for total antioxidant levels. Statistical analysis: For intergroup comparison, Mann–Whitney test was used, and for intragroup comparison, Wilcoxon signed-rank test was used. Results: In the intergroup comparison of both the salivary flow rate and total antioxidant levels, there was no statistically significant difference; however, there was statistically significant difference in the intragroup comparison of salivary flow rate and total antioxidant levels in case group. Conclusions: There was a diminished unstimulated salivary flow rate in ED group, but stimulated salivary flow rate was significantly high and the total antioxidant levels in unstimulated saliva of the case group were significantly higher than the stimulated antioxidant levels.http://www.contempclindent.org/article.asp?issn=0976-237X;year=2019;volume=10;issue=1;spage=74;epage=80;aulast=Mohananectodermal dysplasiasalivary flow ratetotal antioxidant levels
spellingShingle Aravind Mohanan
Balagopal R Varma
Suresh Kumar
Parvathy Kumaran
Arun Mamachan Xavier
Assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients: An In vivo study
Contemporary Clinical Dentistry
ectodermal dysplasia
salivary flow rate
total antioxidant levels
title Assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients: An In vivo study
title_full Assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients: An In vivo study
title_fullStr Assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients: An In vivo study
title_full_unstemmed Assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients: An In vivo study
title_short Assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients: An In vivo study
title_sort assessment of salivary flow rate and antioxidant levels in ectodermal dysplasia patients an in vivo study
topic ectodermal dysplasia
salivary flow rate
total antioxidant levels
url http://www.contempclindent.org/article.asp?issn=0976-237X;year=2019;volume=10;issue=1;spage=74;epage=80;aulast=Mohanan
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