The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus Larvae

Limnothrix (strain AC0243) is a cyanobacterium, which has only recently been identified as toxin producing. Under laboratory conditions, Bufo marinus larvae were exposed to 100,000 cells mL−1 of Limnothrix (strain AC0243) live cultures for seven days. Histological examinations were conducted post mo...

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Main Authors: Olivia Daniels, Larelle Fabbro, Sandrine Makiela
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/6/3/1021
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author Olivia Daniels
Larelle Fabbro
Sandrine Makiela
author_facet Olivia Daniels
Larelle Fabbro
Sandrine Makiela
author_sort Olivia Daniels
collection DOAJ
description Limnothrix (strain AC0243) is a cyanobacterium, which has only recently been identified as toxin producing. Under laboratory conditions, Bufo marinus larvae were exposed to 100,000 cells mL−1 of Limnothrix (strain AC0243) live cultures for seven days. Histological examinations were conducted post mortem and revealed damage to the notochord, eyes, brain, liver, kidney, pancreas, gastrointestinal tract, and heart. The histopathological results highlight the toxicological impact of this strain, particularly during developmental stages. Toxicological similarities to β-N-Methylamino-L-alanine are discussed.
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spelling doaj.art-d8d638551bb5445e8a93bb0250b0f7c72022-12-22T03:58:36ZengMDPI AGToxins2072-66512014-03-01631021103510.3390/toxins6031021toxins6031021The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus LarvaeOlivia Daniels0Larelle Fabbro1Sandrine Makiela2School of Medical and Applied Sciences, Central Queensland University, Rockhampton 4701, AustraliaSchool of Medical and Applied Sciences, Central Queensland University, Rockhampton 4701, AustraliaSchool of Medical and Applied Sciences, Central Queensland University, Rockhampton 4701, AustraliaLimnothrix (strain AC0243) is a cyanobacterium, which has only recently been identified as toxin producing. Under laboratory conditions, Bufo marinus larvae were exposed to 100,000 cells mL−1 of Limnothrix (strain AC0243) live cultures for seven days. Histological examinations were conducted post mortem and revealed damage to the notochord, eyes, brain, liver, kidney, pancreas, gastrointestinal tract, and heart. The histopathological results highlight the toxicological impact of this strain, particularly during developmental stages. Toxicological similarities to β-N-Methylamino-L-alanine are discussed.http://www.mdpi.com/2072-6651/6/3/1021LimnothrixGeitlerinematoxiccyanobacteriahistologyBufo marinusnotochordbrainliverpancreasBMAA
spellingShingle Olivia Daniels
Larelle Fabbro
Sandrine Makiela
The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus Larvae
Toxins
Limnothrix
Geitlerinema
toxic
cyanobacteria
histology
Bufo marinus
notochord
brain
liver
pancreas
BMAA
title The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus Larvae
title_full The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus Larvae
title_fullStr The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus Larvae
title_full_unstemmed The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus Larvae
title_short The Effects of the Toxic Cyanobacterium Limnothrix (Strain AC0243) on Bufo marinus Larvae
title_sort effects of the toxic cyanobacterium limnothrix strain ac0243 on bufo marinus larvae
topic Limnothrix
Geitlerinema
toxic
cyanobacteria
histology
Bufo marinus
notochord
brain
liver
pancreas
BMAA
url http://www.mdpi.com/2072-6651/6/3/1021
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