A Volatile and Dynamic Longitudinal Microbiome Is Associated With Less Reduction in Lung Function in Adolescents With Cystic Fibrosis

A Volatile and Dynamic Longitudinal Microbiome Is Associated With Less Reduction in Lung Function in Adolescents With Cystic Fibrosis

Progressive impairment in lung function caused by chronic polymicrobial airway infection remains the major cause of death in patients with cystic fibrosis (CF). Cross-sectional studies suggest an association between lung function decline and specific lung microbiome ecotypes. However, longitudinal s...

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Bibliographic Details
Main Authors: Marisa I. Metzger, Simon Y. Graeber, Mirjam Stahl, Olaf Sommerburg, Marcus A. Mall, Alexander H. Dalpke, Sébastien Boutin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
lung microbiome
cystic fibrosis
longitudinal study
volatility analysis
Pseudomonas aeruginosa
adolescent
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.763121/full

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