Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report
Fusarium species manifests as an opportunistic infection with intrinsic resistance to most antifungals. We present a case of a 63-year-old male with myelodysplasia who received allogeneic stem cell transplantation and presented with endophthalmitis as the initial manifestation of invasive fusariosis...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Medical Mycology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753923000064 |
| _version_ | 1797818388257439744 |
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| author | Andrew S. Kao Cassondra Cramer-Bour William Kupsky Ayman O. Soubani |
| author_facet | Andrew S. Kao Cassondra Cramer-Bour William Kupsky Ayman O. Soubani |
| author_sort | Andrew S. Kao |
| collection | DOAJ |
| description | Fusarium species manifests as an opportunistic infection with intrinsic resistance to most antifungals. We present a case of a 63-year-old male with myelodysplasia who received allogeneic stem cell transplantation and presented with endophthalmitis as the initial manifestation of invasive fusariosis that progressed to a fatal outcome despite combined intravitreal and systemic antifungal therapies. We urge clinicians to consider this complication of fusarium infection especially with the widespread use of antifungal prophylaxis that may incur selection of more resistant, invasive fungal species. |
| first_indexed | 2024-03-13T09:07:16Z |
| format | Article |
| id | doaj.art-d8df3a50559d4943875b11a8eb9818df |
| institution | Directory Open Access Journal |
| issn | 2211-7539 |
| language | English |
| last_indexed | 2024-03-13T09:07:16Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj.art-d8df3a50559d4943875b11a8eb9818df2023-05-28T04:08:52ZengElsevierMedical Mycology Case Reports2211-75392023-06-014057Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case reportAndrew S. Kao0Cassondra Cramer-Bour1William Kupsky2Ayman O. Soubani3Wayne State University School of Medicine, 540 E. Canfield St, Detroit, 48201, United StatesDetroit Medical Center, Department of Pulmonary and Critical Care Medicine, 3990 John R- 3 Hudson, Detroit, MI, 48201, United StatesDetroit Medical Center, Department of Pathology, 4201 St Antoine, Detroit, MI, 48201, United StatesDetroit Medical Center, Department of Pulmonary and Critical Care Medicine, 3990 John R- 3 Hudson, Detroit, MI, 48201, United States; Corresponding author.Fusarium species manifests as an opportunistic infection with intrinsic resistance to most antifungals. We present a case of a 63-year-old male with myelodysplasia who received allogeneic stem cell transplantation and presented with endophthalmitis as the initial manifestation of invasive fusariosis that progressed to a fatal outcome despite combined intravitreal and systemic antifungal therapies. We urge clinicians to consider this complication of fusarium infection especially with the widespread use of antifungal prophylaxis that may incur selection of more resistant, invasive fungal species.http://www.sciencedirect.com/science/article/pii/S2211753923000064Transplant medicineOpportunistic infectionAntifungal resistance |
| spellingShingle | Andrew S. Kao Cassondra Cramer-Bour William Kupsky Ayman O. Soubani Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report Medical Mycology Case Reports Transplant medicine Opportunistic infection Antifungal resistance |
| title | Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report |
| title_full | Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report |
| title_fullStr | Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report |
| title_full_unstemmed | Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report |
| title_short | Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report |
| title_sort | endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient a case report |
| topic | Transplant medicine Opportunistic infection Antifungal resistance |
| url | http://www.sciencedirect.com/science/article/pii/S2211753923000064 |
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