Multiple Post-SARS-COV2 Infectious Complications in Kidney Transplant Recipient
A forty-seven-year-old recipient in late period after kidney transplantation with chronic estimated glomerular filtration rate (eGFR) 30 mL/min/1.73 m<sup>2</sup>, fully vaccinated against COVID-19 was diagnosed with SARS-CoV-2 infection in November 2021. After an initially mild course o...
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| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/10/1370 |
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| author | Patrycja Grzejszczak Agnieszka Płuciennik Anna Kumor-Kisielewska Ilona Kurnatowska |
| author_facet | Patrycja Grzejszczak Agnieszka Płuciennik Anna Kumor-Kisielewska Ilona Kurnatowska |
| author_sort | Patrycja Grzejszczak |
| collection | DOAJ |
| description | A forty-seven-year-old recipient in late period after kidney transplantation with chronic estimated glomerular filtration rate (eGFR) 30 mL/min/1.73 m<sup>2</sup>, fully vaccinated against COVID-19 was diagnosed with SARS-CoV-2 infection in November 2021. After an initially mild course of the disease, he developed multiorgan failure requiring periodic respiratory and dialysis therapy. Covid-19 disease was complicated by multiple infections such <i>Clostridioides difficile</i> infection, <i>Streptococcus epidermidis</i> bacteriemia, <i>Klebsiella pneumoniae</i> and <i>Candida glabrata</i> urinary tract disease, cytomegalovirus infection and oral candidiasis. In a short period, he was readmitted to the hospital twice with recurrent <i>Klebsiella pneumoniae</i> urosepsis. One of those hospitalizations was also complicated by another COVID-19 infection that was confirmed with non-reactive neutralizing antibody. Due to severe infections the patient required individualized modification of immunotherapy; however, due to their recurrence it was finally decided to be discontinued. The patient was also reintroduced to hemodialysis therapy and no infections occurred since then. |
| first_indexed | 2024-03-09T19:51:38Z |
| format | Article |
| id | doaj.art-d8e030ae5f8340a9b0e52d1158497ce8 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T19:51:38Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-d8e030ae5f8340a9b0e52d1158497ce82023-11-24T01:09:58ZengMDPI AGMedicina1010-660X1648-91442022-09-015810137010.3390/medicina58101370Multiple Post-SARS-COV2 Infectious Complications in Kidney Transplant RecipientPatrycja Grzejszczak0Agnieszka Płuciennik1Anna Kumor-Kisielewska2Ilona Kurnatowska3Department of Internal Medicine and Transplant Nephrology, Medical University of Lodz, 90-153 Lodz, PolandDepartment of Nephrology, Barlicki Memorial Teaching Hospital No. 1, 90-153 Lodz, PolandDepartment of Pathobiology of Respiratory Diseases, Medical University of Lodz, 90-153 Lodz, PolandDepartment of Internal Medicine and Transplant Nephrology, Medical University of Lodz, 90-153 Lodz, PolandA forty-seven-year-old recipient in late period after kidney transplantation with chronic estimated glomerular filtration rate (eGFR) 30 mL/min/1.73 m<sup>2</sup>, fully vaccinated against COVID-19 was diagnosed with SARS-CoV-2 infection in November 2021. After an initially mild course of the disease, he developed multiorgan failure requiring periodic respiratory and dialysis therapy. Covid-19 disease was complicated by multiple infections such <i>Clostridioides difficile</i> infection, <i>Streptococcus epidermidis</i> bacteriemia, <i>Klebsiella pneumoniae</i> and <i>Candida glabrata</i> urinary tract disease, cytomegalovirus infection and oral candidiasis. In a short period, he was readmitted to the hospital twice with recurrent <i>Klebsiella pneumoniae</i> urosepsis. One of those hospitalizations was also complicated by another COVID-19 infection that was confirmed with non-reactive neutralizing antibody. Due to severe infections the patient required individualized modification of immunotherapy; however, due to their recurrence it was finally decided to be discontinued. The patient was also reintroduced to hemodialysis therapy and no infections occurred since then.https://www.mdpi.com/1648-9144/58/10/1370kidney transplantationSARS-CoV-2multi-pathogenic infections |
| spellingShingle | Patrycja Grzejszczak Agnieszka Płuciennik Anna Kumor-Kisielewska Ilona Kurnatowska Multiple Post-SARS-COV2 Infectious Complications in Kidney Transplant Recipient Medicina kidney transplantation SARS-CoV-2 multi-pathogenic infections |
| title | Multiple Post-SARS-COV2 Infectious Complications in Kidney Transplant Recipient |
| title_full | Multiple Post-SARS-COV2 Infectious Complications in Kidney Transplant Recipient |
| title_fullStr | Multiple Post-SARS-COV2 Infectious Complications in Kidney Transplant Recipient |
| title_full_unstemmed | Multiple Post-SARS-COV2 Infectious Complications in Kidney Transplant Recipient |
| title_short | Multiple Post-SARS-COV2 Infectious Complications in Kidney Transplant Recipient |
| title_sort | multiple post sars cov2 infectious complications in kidney transplant recipient |
| topic | kidney transplantation SARS-CoV-2 multi-pathogenic infections |
| url | https://www.mdpi.com/1648-9144/58/10/1370 |
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